96304-35-7Relevant academic research and scientific papers
DIASTEREOFACE-DIFERENTIATING ADDITION OF ORGANOMETALLICS TOWARD CHIRAL α-KETOENAMINES
Fujisawa, Tamotsu,Watanabe, Makoto,Sato, Toshio
, p. 2055 - 2058 (1984)
The diastereoface-differentiating reaction of Grignard reagents or organolithium reagents toward chiral cyclic α-ketoenamines, prepared from the corresponding cycloalkane-1,2-dione and optically active pyrrolidine derivatives, was found to give, after hydrolysis, (R)- or (S)-α-hydroxycycloalkanones, respectively, in high enantiomeric excess.
