96306-50-2

Upstream product

• 83-72-7 2-hydroxynaphtho-1,4-quinone 
• 100-52-7 benzaldehyde 
• 774-48-1 (diethoxymethyl)benzene 
• 63534-43-0 rac-2-hydroxy-2,3-dihydronaphthalene-1,4-dione 

Downstream Products

• 24055-77-4 7-phenyl-6H-dibenzo[b,h]xanthene-5,6,8,13(7H)-tetraone 
• 1059626-75-3 13-phenyl-5H-dibenzo[b,i]xanthene-5,7,12,14-(13H)-tetraone 

Relevant academic research and scientific papers

Inhibition of Zika virus replication by synthetic bis-naphthoquinones

Zika virus (ZIKV) is a mosquito-borne pathogen which is a current global public health concern. There are currently no approved vaccines or antivirals against ZIKV infection. Taking into account that naphthoquinones have shown promising antiviral activity

A highly efficient and green protocol for the synthesis of 3,3′-(arylmethylene)-bis(2-hydroxynaphthoquinone) derivatives catalyzed by a dicationic molten salt

A highly efficient and green protocol for the synthesis of 3,3′-(arylmethylene)-bis(2-hydroxynaphthoquinone) {3,3′-(arylmethylene)-bis(2-hydroxynaphthalene-1,4-dione)} derivatives has been developed. The reaction of 2-hydroxynaphthoquinone (2-hydroxynapht

Highly efficacious preparation of 3,3′-(arylmethylene)-bis(2-hydroxynaphthoquinone) derivatives catalyzed by a nanorod-structured organic–inorganic hybrid material

Abstract: A nanorod-structured organic–inorganic hybrid material namely nanorod-[SiO2–Pr–Im–SO3H][CF3CO2] (N-[SPIS][TFA]) has been applied as a highly efficacious, dual-functional, and recoverable catalyst for t

Lipase catalyzed synthesis of 3,3′-(arylmethylene)bis(2- hydroxynaphthalene-1,4-dione)

As a green and inexpensive biocatalyst, lipase has been used to catalyze the synthesis of 3,3′-(arylmethylene)bis(2-hydroxynaphthalene-1,4-dione) (3) for the first time. The products could be obtained in excellent yields (82.2-94.8%, 2 h). This study not

3,3′-(Arylmethylene)bis(2-hydroxynaphthalene-1,4-dione) as the main product of the Mannich reaction of 2-hydroxy-1,4-naphthoquinone with 4H-1,2,4-triazol-4-amine and various aldehydes

The Mannich reaction of lawsone with various aldehydes and 4H-1,2,4-triazol-4-amine gave unexpected 3,3′-(arylmethylene)bis(2-hydroxynaphthalene-1,4-dione)derivatives.With2,4-dihydroxybenzaldehydeunderthesameconditions,itledtotheformationof3-hydroxy-12-(3

An efficient approach to bis-benzoquinonylmethanes on water under catalysis of the bio-derived O-carboxymethyl chitosan

Synthesis of the dyes 3,3′-(arylmethylene)bis(2-hydroxynaphthalene-1,4-diones) was achieved efficiently in mild and metal-free conditions from a pseudo three-component reaction between 2-hydroxynaphthalene-1,4-dione and aldehydes under catalysis of O-carb

Insight into and Computational Studies of the Selective Synthesis of 6H-Dibenzo[b,h]xanthenes

Starting from 2-hydroxy-1,4-naphthoquinone (lawsone), we synthesized eight new 6H-dibenzo[b,h]xanthene derivatives selectively under solvent-free conditions. Spectroscopic investigations confirmed that only the isomer 6H-dibenzo[b,h]xanthene was obtained

Selective pro-apoptotic activity of novel 3,3′-(aryl/alkyl-methylene)bis(2-hydroxynaphthalene-1,4-dione) derivatives on human cancer cells via the induction reactive oxygen species

Selective induction of apoptosis in cancer cells barring the normal cells is considered as an effective strategy to combat cancer. In the present study, a series of twenty-two (22) synthetic 3,3′-(aryl/alkyl-methylene)bis(2-hydroxynaphthalene-1,4-dione) b

Acid catalyzed efficient syntheses of aryl-5H-dibenzo[b,i]xanthene-5,7,12,14-(13H)-tetraones and 3,3-(arylmethylene)bis(2-hydroxynaphthalene-1,4-diones) and in vitro evaluation of their antioxidant activity

A simple and efficient synthesis of aryl-5H-dibenzo[b,i]xanthene-5,7,12,14-(13H)-tetraones and 3, 3-(arylmethylene)bis(2-hydroxynaphthalene-1,4-diones) by the condensation of aromatic aldehydes and 2-hydroxy-1,4-naphthoquinone under extremely mild conditi

Antileishmanial activity evaluation of bis-lawsone analogs and DNA topoisomerase-I inhibition studies

For the development of potent novel antileishmanial agents, 3,3′-(arylmethylene)bis(2-hydroxynaphthalene-1,4 dione) derivatives were synthesized from lawsone and evaluated for cytotoxicity on Leishmania donovani promastigotes as well as on leishmanial DNA