96315-16-1

Usage

Uses

Used in Pharmaceutical Industry:
Benzoic acid, 4-(bromomethyl)-3-nitro-, ethyl ester is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the formation of complex organic compounds that can have medicinal properties.
Used in Fragrance and Flavor Industry:
It may also be utilized in the manufacturing of fragrances and flavors due to its potential to contribute to the creation of various scent and taste profiles.
However, it is crucial to handle Benzoic acid, 4-(bromomethyl)-3-nitro-, ethyl ester with care, as it may pose health and environmental hazards.

Upstream product

• 96-98-0 4-methyl-3-nitrobenzoic acid 
• 55715-03-2 4-bromomethyl-3-nitrobenzoic acid 
• 10397-30-5 4-methyl-3-nitrobenzoyl chloride 
• 19013-15-1 ethyl 4-methyl-3-nitro-benzoate 

Downstream Products

• 365462-69-7 ethyl 4-{[(3-cyanophenyl)amino]methyl}-3-nitrobenzoate 
• 365462-71-1 ethyl 4-formyl-3-nitrobenzoate 
• 861384-91-0 ethyl 4-(3-ethoxy-2,3-dioxopropyl)-3-nitrobenzoate 
• 107516-75-6 diethyl 1H-indole-2,6-dicarboxylate 
• 1494687-39-6 ethyl 3-nitro-4-(3-oxo-3-phenylpropyl)benzoate 
• 1494687-47-6 ethyl 4-(3-bromo-3-phenylpropyl)-3-nitrobenzoate 
• 1018785-26-6 C₂₄H₃₁N₃O₇ 
• 761392-41-0 ethyl 4-[({3-[amino(imino)methyl]phenyl}amino)methyl]-3-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate 
• 840531-40-0 ethyl 4-(2-{3-[amino(imino)methyl]phenyl}ethyl)-3-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate 
• 781605-91-2 4-[(3-carbamimidoyl-phenylamino)-methyl]-3-[4-(4-methyl-[1,4]diazepan-1-yl)-benzoylamino]-benzoic acid 
• 840531-37-5 ethyl 4-({3-[amino(imino)methyl]phenoxy}methyl)-3-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate 
• 365462-88-0 ethyl 4-{[(3-cyanophenyl)amino]methyl}-3-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate 
• 840531-21-7 ethyl 4-[(3-cyanophenoxy)methyl]-3-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate 
• 840531-25-1 ethyl 4-[2-(3-cyanophenyl)ethyl]-3-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate 

Relevant academic research and scientific papers

Design, synthesis and biological evaluation of novel substituted benzoylguanidine derivatives as potent Na+/H+ exchanger inhibitors

A novel series of substituted benzoylguanidine derivatives were designed and synthesized as potent NHE1 inhibitors. Most compounds can significantly inhibit NHE1-mediated platelet swelling in a concentration-dependent manner, among which compound 5f (ICs

AMIDE DERIVATIVE

The present invention provides an amide derivative represented by the following general formula (1): wherein R1 represents a saturated cyclic amino group, R2 represents alkyl, halogen or haloalkyl, R3 represents hydrogen or halogen, Het 2 represents pyridyl or pyrimidinyl, and Het 1 represents a group of the formula [6], or a salt thereof, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention is useful as a BCR-ABL tyrosine kinase inhibitor.

Synthesis and biological activity of novel 1,2-disubstituted benzene derivatives as factor Xa inhibitors

Factor Xa (fXa) is a serine protease that plays a pivotal role in the coagulation cascade. High-throughput screening of the Yamanouchi compound library yielded lead compound 1 with the ability to inhibit fXa at micromolar concentrations. To improve its fX

Design of new fluorinated bridged push-pull stilbenes and preparation of LB films for second harmonic generation in the blue domain

In order to prepare alternating Y-type multilayers involving push-pull stilbenes giving second harmonic generation (SHG) in the blue domain, we have synthesized two new bridged compounds, 1 and 2, with the hydrophobic chain grafted onto the donor group. The photophysical properties of these dyes in both solution and LB films are reported. The SHG signal of monolayer LB films containing 1 and 2 are close to that of the analog 3 and 4 having the hydrophobic chain grafted onto the acceptor group. Finally, multilayer LB films based on one, two and four bilayers of 1/3 or 2/4 were prepared and the SHG measurements show a regular noncentrosymmetric arrangement for 2/4 films only.