96323-05-6

Upstream product

• 337365-53-4 (1S,2S,5'R,1''S)-N,N-diisopropyl-{7,7-dimethyl-2-spiro-2'-[5',5'-(2''-carbomethoxy-1''-methyl)ethylmethyl-1',3'-dioxolane-4'-one]}bicyclo[2.2.1]hept-1-ylmethanesulfonamide 
• 256393-09-6 (1S,2S,5'R)-N,N-diisopropyl [2-spiro-2'-(5'-phenylmethyl-1',3'-dioxolane-4'-one)-7,7-dimethylbicyclo[2.2.1]hept-1-yl]methanesulfonamide 
• 64-17-5 ethanol 
• 256393-12-1 (1S,2S,5'R)-N,N-diisopropyl [2-spiro-2'-(5'-ethyl-5'-methyl-1',3'-dioxolane-4'-one)-7,7-dimethylbicyclo[2.2.1]hept-1-yl]methanesulfonamide 
• 256393-18-7 (1S,2S,5'S)-N,N-diisopropyl {2-spiro-2'-[5'-phenyl-5'-(prop-2''-enyl)-1',3'-dioxolane-4'-one]-7,7-dimethylbicyclo[2.2.1]hept-1-yl}methanesulfonamide 
• 67-56-1 methanol 

Downstream Products

• 150763-94-3 (-)-10-<(N,N-Diisopropylamino)sulfonyl>camphor N-(benzylsulfonyl)imine 
• 1367740-26-8 (2R)-2-benzyl-sulfanyl-2-cyano-7,7-dimethyl-bicyclo[2.2.1]hept-1-yl-N,N-diisopropyl-methane-sulfonamide 
• 1367740-29-1 (2R)-2-aminomethyl-2-benzylsulfanyl-7,7-dimethyl-bicyclo[2.2.1]hept-1-yl-N,N-diisopropyl-methanesulfonamide 
• 1367740-30-4 (2R)-2-benzylsulfanyl-7,7-dimethyl-2-morpholin-4-yl-methyl-bicyclo[2.2.1]hept-1-yl-N,N-diisopropyl-methane-sulfonamide 
• 131248-99-2 C₂₆H₄₁NO₅S 
• 213532-65-1 (Z)-2-[4''-(tert-butyloxycarbonyl)phenyl]-1-[(1'S)-10'-(diisopropylsulfamoyl)isobornylthio]-1-nitroethene 
• 163182-10-3 (1S,2S)-N,N-diisopropyl [2-spiro-2'-(1',3'-dioxolane-4'-one)-7,7-dimethylbicyclo[2.2.1]hept-1-yl]methanesulfonamide 
• 256393-18-7 (1S,2S,5'S)-N,N-diisopropyl {2-spiro-2'-[5'-phenyl-5'-(prop-2''-enyl)-1',3'-dioxolane-4'-one]-7,7-dimethylbicyclo[2.2.1]hept-1-yl}methanesulfonamide 
• 256393-11-0 (1S,2S,5'S)-N,N-diisopropyl [2-spiro-2'-(5'-phenyl-1',3'-dioxolane-4'-one)-7,7-dimethylbicyclo[2.2.1]hept-1-yl]methanesulfonamide 
• 256393-09-6 (1S,2S,5'R)-N,N-diisopropyl [2-spiro-2'-(5'-phenylmethyl-1',3'-dioxolane-4'-one)-7,7-dimethylbicyclo[2.2.1]hept-1-yl]methanesulfonamide 

Relevant academic research and scientific papers

Process for preparing optically active α-hydroxy acids and derivatives thereof

The present invention provides a process for preparing optically active α-hydroxy acids and derivatives thereof by subjecting the alkylated 1,3-dioxolanones of formula (IV) wherein R1and R2are the same or different and are each independently H or C1-6alkyl; R5is H, C1-16alkyl, or unsubstituted or substituted phenyl; and R6is C1-8alkyl, C2-7alkenyl or unsubstituted or substituted benzyl, to either alcoholysis or hydrolysis, in which the alkylated 1,3-dioxolanones are obtained by using 10-camphorsulfonamide as a chiral auxiliary.

Highly diastereoselective Michael addition of α-hydroxy acid derivatives and enantioselective synthesis of (+)-crobarbatic acid

(matrix presented) Michael addition of enolates of 2a and 2b to α,β-unsaturated esters took place selectively on different faces (Si and Re, respectively) of the double bond to give the corresponding products 4 and 5, respectively, with >98% de. Subsequen

Enantioselective synthesis of α-hydroxy acids employing (1S)-(+)-N,N-diisopropyl-10-camphorsulfonamide as chiral auxiliary

matrix presented I R1=H, Me, Ph II (>98 de.) III Lewis acid (BF3·-OEt2) catalyzed condensation of dimethoxy acetal 2 with α-hydroxy acids produces chiral 1,3-dioxolanones I. The enolates derived from these compounds underg