96355-38-3Relevant academic research and scientific papers
Photoredox-Catalyzed Generation of Sulfamyl Radicals: Sulfonamidation of Enol Silyl Ether with Chlorosulfonamide
Luo, Qiyu,Mao, Runyu,Zhu, Yan,Wang, Yonghui
, p. 13897 - 13907 (2019/11/11)
A novel and practical photoredox-catalyzed generation of sulfamyl radicals followed by radical sulfonamidation of enol silyl ether has been described. Diverse functionalized β-ketosulfonamides were prepared in modest to excellent yields under mild and economic reaction conditions through the present catalytic protocol. Furthermore, the methodology developed provides an efficient and convenient approach to the synthesis of the antiseizure drug Zonisamide.
CYCLO-ADDITION REACTIONS OF N-SULPHINYLCARBOXAMIDES. III. REACTIONS OF N-SULPHINYL-p-TOLUAMIDE WITH ALKYNES
Carpanelli, Corrado,Gaiani, Giovanni,Sancassan, Fernando
, p. 265 - 268 (2007/10/02)
N-Sulphinyl-p-toluamide, 1, has been found to behave as a heterodiene towards alkynes in cyclo-addition reactions, giving substituted 1,4,3-oxathiazine 4-oxides, 2.With 1-alkynes the reaction took place regioselectively, yielding 6-substituted cyclo-adducts.The oxidation of compounds 2 gave the corresponding 4,4-dioxides 3 and some of the latter subjected to ring opening by hydrolysis or reduction.
