964-25-0

Basic information

• Product Name: 6-nitro-3-phenyl-4(3H)-quinazolinone
• Synonyms: 6-nitro-3-phenyl-4(3H)-quinazolinone
• CAS NO: 964-25-0
• Molecular Weight: 267.244
• Mol File: 964-25-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 6-nitro-3-phenyl-4(3H)-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 6-nitro-3-phenyl-4(3H)-quinazolinone(964-25-0)
• EPA Substance Registry System: 6-nitro-3-phenyl-4(3H)-quinazolinone(964-25-0)

Safety Data

• Hazardous Substances Data: 964-25-0(Hazardous Substances Data)

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 30481-54-0 2-amino-5-nitro-N-phenylbenzamide 
• 75-91-2 tert.-butylhydroperoxide 
• 122-51-0 orthoformic acid triethyl ester 
• 62-53-3 aniline 
• 616-79-5 2-amino-5-nitro-benzoic acid 
• 80-43-3 bis(1-methyl-1-phenylethyl)peroxide 

Relevant articles and documents

N,N-Dimethylformamide as Carbon Synthons for the Synthesis ofN-Heterocycles: Pyrrolo/Indolo[1,2-a]quinoxalines and Quinazolin-4-ones

N,N-dimethylformamide (DMF) as synthetic precursors contributing especially the methyl, acyl, and amino groups has played a significant role in heterocycle syntheses and functionalization. In this protocol, a wide range of pyrrolo/indolo[1,2-a]quinoxalines and quinazolin-4-ones were obtained in moderate to good yields by using elemental iodine without any metal or peroxides. We considered thatN-methyl andN-acyl of DMF participate and complete the reaction separately through different mechanisms, which displayed potential still to be explored of DMF.

Discovery of molluscicidal and cercaricidal activities of 3-substituted quinazolinone derivatives by a scaffold hopping approach using a pseudo-ring based on the intramolecular hydrogen bond formation

Discovery of novel topological agents against Oncomelania hupensis snails and cercariae remains a significant challenge in current Schistosomiasis control. A pseudo-ring formed from salicylanilide by an intramolecular hydrogen bond led to the discovery of 3-substituted quinazolinone derivatives which showed a potent molluscicidal and cercaricidal activities.

Eco-friendly, solvent-free novel one-pot, three-component synthesis of quinazolinones at ambient temperature catalyzed by silica gel-supported phosphomolybdic acid

(Chemical Presented) Silica gel supported Phosphomolybdic acid (PMA.SiO2) catalyzes efficiently the one-pot three-component coupling reaction of anthranilic acid, orthoesters, and amines at room temperature to afford 4(3H)-Quinazolinones in hig