96400-68-9Relevant academic research and scientific papers
Applications of a novel carbon-nitrogen bond cleavage reaction: Part IV - A new biomimetic synthesis of benzo[c]phenanthridine alkaloids
Lal, Bansi,Gidwani, Ramesh M.
, p. 679 - 681 (2007/10/03)
A highly practical synthesis of benzo[c]phenanthridine alkaloids nitidine and 2-methoxyfagaronine has been developed from the corresponding protoberberines. The 8-oxoprotoberberines 1-3 on reaction with NaH and DMF give the C-N bond cleavage intermediates
TRANSFORMATION OF PROTOBERBERINES INTO BENZOPHENANTHRIDINES A NOVEL AND EFFICIENT SYNTHESIS OF ANTITUMOR BENZOPHENANTHRIDINE ALKALOIDS, FAGARONINE AND NITIDINE
Hanaoka, Miyoji,Yamagishi, Hiroshi,Marutani, Mari,Mukai, Chisato
, p. 5169 - 5172 (2007/10/02)
Antileukemic benzophenanthridine alkaloids, fagaronine (1a) and nitidine (1c) were synthesized from the corresponding protoberberines through C6-N bond fission and subsequent cyclization between C6 and C13 position of the protoberberines.
