96432-53-0Relevant academic research and scientific papers
Usual and unusual reactions of cyclohexane-1,2-dione with aryl azides and amines: a structural corrigendum
Singh, Neeraj,Banert, Klaus
supporting information, p. 1897 - 1901 (2017/03/09)
The reported syntheses of alleged functionalised 1,2,3-triazines from cyclohexane-1,2-dione and aryl azides, in the presence of pyrrolidine and other amines, were repeated. The products do not contain the bicyclic triazine and bicyclic ketone moieties; instead, cyclohexane-fused 4,5-dihydro-1,2,3-triazoles and monocyclic β-ketoamides were obtained, respectively. These corrections are well supported by careful analyses of NMR spectra, IR spectra, elemental analysis and comparison with data which were previously published in the literature. Suitable mechanisms are discussed for the synthesis of the observed compounds.
Highly Diastereo- and Enantioselective Synthesis of α-Spiro-δ-lactams by an Organocascade Reaction
Zhang, Kaiheng,Meazza, Marta,Do?ekal, Vojtěch,Light, Mark E.,Vesely, Jan,Rios, Ramon
supporting information, p. 1749 - 1756 (2017/04/13)
An asymmetric synthesis of α-spiro-δ-lactams by an organocascade reaction of easily accessible starting materials has been accomplished. The catalytic sequence begins with enantioselective Michael addition of a β-ketoamide to an α,β-unsaturated aldehyde,
HETEROCYCLIC SUBSTITUTED PIPERAZINES FOR THE TREATMENT OF SCHIZOPHRENIA
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Page 139, (2010/02/06)
This invention relates to compounds of the formula 1 wherein X, Y, Z, A, R', R2, R3, R4, R9, W' and W2 are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system and other diso
Dihydroquinolines as novel n-NOS inhibitors
Jaroch, Stefan,Hoelscher, Peter,Rehwinkel, Hartmut,Suelzle, Detlev,Burton, Gerardine,Hillmann, Margrit,McDonald, Fiona M.
, p. 2561 - 2564 (2007/10/03)
Dihydroquinolines have been synthesized and have been shown to be potent n-NOS inhibitors. Selectivity versus e-NOS was increased to approximately 100-fold through appropriate substitution at the benzene ring.
