96447-05-1

Basic information

• Product Name: 2-oxo-cyclopentanecarboxylic acid p-toluidide
• Synonyms: 2-oxo-cyclopentanecarboxylic acid p-toluidide
• CAS NO: 96447-05-1
• Molecular Weight: 217.268
• Mol File: 96447-05-1.mol

Chemical Properties

• CAS DataBase Reference: 2-oxo-cyclopentanecarboxylic acid p-toluidide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-oxo-cyclopentanecarboxylic acid p-toluidide(96447-05-1)
• EPA Substance Registry System: 2-oxo-cyclopentanecarboxylic acid p-toluidide(96447-05-1)

Safety Data

• Hazardous Substances Data: 96447-05-1(Hazardous Substances Data)

Upstream product

• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 106-49-0 p-toluidine 
• 32961-64-1 4,5,6,7-tetrahydrocyclopenta-1,3-dioxin-4-one 
• 936-52-7 1-(N-morpholino)cyclopent-1-ene 
• 622-58-2 p-Tolylisocyanate 
• 2101-86-2 p-methylazidobenzene 
• 765-87-7 cyclohexane-1,2-dione 

Relevant articles and documents

Usual and unusual reactions of cyclohexane-1,2-dione with aryl azides and amines: a structural corrigendum

The reported syntheses of alleged functionalised 1,2,3-triazines from cyclohexane-1,2-dione and aryl azides, in the presence of pyrrolidine and other amines, were repeated. The products do not contain the bicyclic triazine and bicyclic ketone moieties; instead, cyclohexane-fused 4,5-dihydro-1,2,3-triazoles and monocyclic β-ketoamides were obtained, respectively. These corrections are well supported by careful analyses of NMR spectra, IR spectra, elemental analysis and comparison with data which were previously published in the literature. Suitable mechanisms are discussed for the synthesis of the observed compounds.

Dihydroquinolines as novel n-NOS inhibitors

Dihydroquinolines have been synthesized and have been shown to be potent n-NOS inhibitors. Selectivity versus e-NOS was increased to approximately 100-fold through appropriate substitution at the benzene ring.