96459-82-4Relevant academic research and scientific papers
A Convenient Synthesis of Fluoroalkylated Benzimidazole- or Indole-fused Benzoxazines
Cao, Weiguo,Chen, Jie,Deng, Hongmei,Hu, Yijie,Li, Jianyang,Li, Na,Lin, Jin-Hong,Ren, Nan,Wang, Xiaoli,Zhang, Hui
supporting information, (2022/02/16)
Fluoroalkyl group is of particular interest in pharmaceutical chemistry. Since benzimidazole- or indole-fused benzoxazines are important motifs in numerous biologically active molecules, the incorporation of a fluoroalkyl group into these molecules may provide more opportunities for drug developments. Herein we describe the first synthesis of fluoroalkylated benzimidazole- or indole-fused benzoxazines by using fluoroalkylated propiolates as building blocks. The reactions proceeded smoothly under mild conditions to give the desired products in moderate to high yields. Notably, benzimidazole-fused products were obtained by a convenient one-pot two-step process.
2-(2'-Hydroxyphenyl)benzothiazoles, -benzoxazoles, and -benzimidazoles for Plastic Scintillation Applications
Pla-Dalmau, Anna
, p. 5468 - 5473 (2007/10/02)
A new series of fluorescent compounds has been tested as dopants for plastic scintillation applications.Several 2-(2'-hydroxyphenyl)benzothiazole, -benzoxazole, and -benzimidazole derivative have been prepared and studied in a polystyrene matrix.Each deri
