96481-07-1

Basic information

• Product Name: (25S)-3β,26-dihydroxycholest-5-en-16-one
• CAS NO: 96481-07-1
• Molecular Weight: 416.645
• Mol File: 96481-07-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (25S)-3β,26-dihydroxycholest-5-en-16-one(CAS DataBase Reference)
• NIST Chemistry Reference: (25S)-3β,26-dihydroxycholest-5-en-16-one(96481-07-1)
• EPA Substance Registry System: (25S)-3β,26-dihydroxycholest-5-en-16-one(96481-07-1)

Safety Data

• Hazardous Substances Data: 96481-07-1(Hazardous Substances Data)

Upstream product

• 113917-66-1 (25S)-3β,26-bis-p-nitrobenzoyloxycholest-5-en-16β-ol 
• 53755-50-3 (25S)-cholest-5-ene-3β,16β,26-triol 
• 1061-54-7 yamogenin-acetate 
• 470-05-3 diosgenin 
• 113917-67-2 (25S)-3,26-bis-p-nitrobenzoylcholest-5-en-16-one 

Downstream Products

• 105078-98-6 (25S)-3β-acetoxy-26-trityloxycholest-5-ene 
• 113917-72-9 (25S)-3-acetoxy-26-tosyloxycholest-5-ene 
• 113917-68-3 C₄₇H₆₀F₆O₆ 
• 113917-68-3 C₄₇H₆₀F₆O₆ 
• 13095-61-9 (25R)-cholest-5-ene-3β,26-diol 

Relevant articles and documents

SYNTHESIS OF (25R)-CHOLESTEROL AND 1H N.M.R. AND H.P.L.C. RESOLUTION OF (25R)- AND (25S)-26-HYDROXYCHOLESTEROL

Yamogenin acetate (1) was isolated from crude diosgenin acetate and converted into (25S)-26-hydroxycholesterol (6a).The absolute configuration at C-25 of (6a) was determined by X-ray crystallography. (25R)-Cholesterol (10) was prepared by reduction of the 26-tosyloxy group by LiAl(2)H4.Reverse-phase h.p.l.c. resolution without derivatization was developed for the diastereoisomers, (25R)- and (25S)-26-hydroxycholesterol.The (+)- or (-)-MTPA esters of these diastereoisomers showed distinctive 1H n.m.r. signals for 26-H.