96488-05-0Relevant academic research and scientific papers
Ene approach to asymmetric catalysis of the "Sakurai-Hosomi reaction", Lewis acid-promoted carbonyl-addition reaction with allylic silanes
Mikami, Koichi,Matsukawa, Satoru
, p. 3133 - 3136 (1994)
The chiral Lewis acid prepared from (R)-binaphthol and diisopropoxytitanium dichloride catalyzes the reaction of glyoxylate esters with methallylsilanes to afford mainly ene-type products rather than the products expected from the "usual" Sakurai-Hosomi r
A facile synthesis of chiral ω-allyl- and ω-n-propyllactones via asymmetric allylboration of formyl esters with B- allyldiisopinocampheylborane
Ramachandran, P. Veeraraghavan,Krzeminski, Marek P.,Reddy, M. Venkat Ram,Brown, Herbert C.
, p. 11 - 15 (2007/10/03)
Asymmetric allylboration of aldehydes containing an adjacent ester group with B-allyldiisopinocampheylborane, followed by hydrolysis and cyclization, provides the corresponding allyl substituted lactones in high yields and ≥92% enantiomeric excess. Hydrogenation of these lactones provides the corresponding propyl substituted lactones without any loss of optical purity.
ASYMMETRIC WITTIG REARRANGEMENT INVOLVING CHIRAL POTASSIUM AZAENOLATES. THE DRAMATIC INFLUENCE OF THE POTASSIUM COUNTERION AND ITS COMPLEXATION WITH 18-CROWN-6
Mikami, Koichi,Kasuga, Takashi,Fujimoto, Katsuhiko,Nakai, Takeshi
, p. 4185 - 4188 (2007/10/02)
The diastereoface selection is described in the title rearrangement of chiral 2-oxazoline systems either in the absence or the presence of 18-crown-6.The dramatic effects of the K (1+) counterion and its complexation with the crown ether are noted.
