96490-18-5

Basic information

• Product Name: 4-CHLORO-2-(1,1-DIMETHYLETHYL)-5-MERCAPTO-3(2H)-PYRIDAZINONE
• Synonyms: 4-CHLORO-2-(1,1-DIMETHYLETHYL)-5-MERCAPTO-3(2H)-PYRIDAZINONE
• CAS NO: 96490-18-5
• Molecular Formula: C₈H₁₁ClN₂OS
• Molecular Weight: 218.70374
• Mol File: 96490-18-5.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-CHLORO-2-(1,1-DIMETHYLETHYL)-5-MERCAPTO-3(2H)-PYRIDAZINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2-(1,1-DIMETHYLETHYL)-5-MERCAPTO-3(2H)-PYRIDAZINONE(96490-18-5)
• EPA Substance Registry System: 4-CHLORO-2-(1,1-DIMETHYLETHYL)-5-MERCAPTO-3(2H)-PYRIDAZINONE(96490-18-5)

Safety Data

• Hazardous Substances Data: 96490-18-5(Hazardous Substances Data)

Usage

Uses

4-Chloro-2-(1,1-dimethylethyl)-5-mercapto-3(2H)-pyridazinone is an intermediate used in the synthesis of Pyridaben is a pyridazinone derivative used as an insecticide and acaricide. In the European Union, Pyridaben has been authorized for use as an insecticide and acaricide from 1 May 2011. In Germany, Austria and Switzerland, no plant protection products containing this active substance are authorized. Pyridaben is a colorless solid that is practically insoluble in water. Cannabis testing.

Upstream product

• 7440-44-0 pyrographite 
• 84956-71-8 2-tert-butyl-4,5-dichloro-2H-pyridazin-3-one 

Downstream Products

• 141604-31-1 2-tert-butyl-4-chloro-5-(4-isopropoxymethyl-cyclohexyl)-methylthio-3(2H)-pyridazinone 
• 141604-36-6 2-tert-butyl-4-chloro-5-(4-n-butoxymethyl-cyclohexyl)methylthio-3(2H)-pyridazinone 
• 96489-71-3 pyridaben 
• 112188-60-0 2-tert-butyl-4-chloro-5-[2-(2,6-dichloro-4-n-propylphenoxy)ethylthio]-3(2H)-pyridazinone 
• 118259-05-5 2-tert-butyl-4-chloro-5-[2-{4-(2-ethylthioethyl)phenoxy}ethylthio]-3(2H)-pyridazinone 
• 118258-60-9 2-tert-butyl-4-chloro-5-[2-{2-methyl-4-(2-methoxyethyl)phenoxy}ethylthio]-3(2H)-pyridazinone 
• 141604-42-4 2-tert-butyl-4-chloro-5-(4-isobutylthiomethylcyclohexyl)methylthio-3(2H)-pyridazinone 
• 141604-33-3 2-tert-butyl-4-chloro-5-[4-(2,2,2-trifluoroethoxymethyl)cyclohexyl]methylthio-3(2H)-pyridazinone 
• 141604-41-3 2-tert-butyl-4-chloro-5-(4-cyclohexylmethoxymethyl-cyclohexyl)methylthio-3(2H)-pyridazinone 
• 141604-40-2 2-tert-butyl-4-chloro-5-(4-cyclohexyloxymethylcyclohexyl)methylthio-3(2H)-pyridazinone 
• 141604-39-9 2-tert-butyl-4-chloro-5-(4-n-hexyloxymethyl-cyclohexyl)methylthio-3(2H)-pyridazinone 
• 141604-34-4 2-tert-butyl-4-chloro-5-(4-cyclopropylmethoxymethyl-cyclohexyl)methylthio-3(2H)-pyridazinone 
• 141604-45-7 2-tert-butyl-4-chloro-5-(4-n-propoxycyclohexyl)-methylthio-3(2H)-pyridazinone 
• 141604-35-5 2-tert-butyl-4-chloro-5-(4-n-propoxymethyl-cyclohexyl)methylthio-3(2H)-pyridazinone 

Relevant articles and documents

Nickel-catalyzed oxidative dehydrogenative coupling of alkane with thiol for C(sp3)-S bond formation

A nickel-catalyzed oxidative dehydrogenative coupling reaction of alkane with thiol for the construction of C(sp3)-S bond has been established, affording more than 50 alkyl thioethers. Notably, pharmaceutical and agrochemicals, such as Provigil, Chlorbenside and Pyridaben, were readily synthesized by this approach. The sterically hindered ligand BC and disulfide which was formed in situ oxidation of thiol, efficiently avoiding nickel-catalyst poisoning. A set of mechanistic experiments disclose both Ni-catalyzed and Ni-free HAA processes.

Pyridazinone derivative, and preparation method and application thereof

The invention relates to a pyridazinone derivative with the structure shown in the description. R1 and R2 groups in the structure are selected from specific groups in the description. The invention discloses the structure of the compound, and an agriculture pest prevention and control effect of the compound, and also discloses an application of the compound as a pesticide.

Synthesis and antifeedant activity of new oxadiazolyl 3(2H)-pyridazinones

A total of 20 new compounds containing the oxadiazolyl 3(2H)-pyridazinone moiety were synthesized. The structures of all the compounds were confirmed by 1H NMR, IR, MS, and elemental analysis. Their insect antifeedant activities against Asiatic corn borer Ostrinia furnacalis (Guenee) were examined and compared with commercial azadirachtin. The compounds exhibited significant levels of activity. The feeding deterrency values of IIIa,j were 57% and 51% at 500 mg/kg concentration, respectively.