96517-13-4Relevant academic research and scientific papers
Copper-catalyzed/promoted cross-coupling of gem -diborylalkanes with nonactivated primary Alkyl halides: An alternative route to alkylboronic esters
Zhang, Zhen-Qi,Yang, Chu-Ting,Liang, Lu-Jun,Xiao, Bin,Lu, Xi,Liu, Jing-Hui,Sun, Yan-Yan,Marder, Todd B.,Fu, Yao
supporting information, p. 6342 - 6345 (2015/01/16)
The first copper-catalyzed/promoted sp3-C Suzuki-Miyaura coupling reaction of gem-diborylalkanes with nonactivated electrophilic reagents is reported. Not only 1, 1-diborylalkanes but also some other gem-diborylalkanes can be coupled with nonactivated primary alkyl halides, offering a new method for sp3C-sp3C bond formation and, simultaneously, providing a new strategy for the synthesis of alkylboronic esters.
Leukotriene B4 (LTB4) receptor antagonists: a series of (hydroxyphenyl)pyrazoles.
Harper,Jackson,Froelich,Boyd,Aldridge,Herron
, p. 2411 - 2420 (2007/10/02)
A series of (hydroxyphenyl)pyrazoles was designed by molecular modeling comparison with the LTB4 structure and prepared for evaluation as LTB4 receptor antagonists, culminating in 4-ethyl-5-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]-2-(1H-pyrazol -3- yl)p
