96540-32-8Relevant academic research and scientific papers
Effect of microwave irradiation on the formation of bicyclic cyclopropane derivatives
Finta, Zoltan,Hell, Zoltan,Toke, Laszlo
, p. 242 - 244 (2007/10/03)
Microwave irradiation changes the diastereomeric composition of the bicyclic cyclopropane carboxylic acid lactones obtained in the intramolecular cyclization of malonic acid allylic esters in a phase transfer catalysed reaction.
Diastereoselectivity in the formation of bicyclic cyclopropane carboxylic acid lactones
Hell, Zoltan,Finta, Zoltan,Gruenvald, Tamas,Boecskei, Zsolt,Balan, Daniella,Keseru, Gyoergy M.,Toke, Laszlo
, p. 1367 - 1376 (2007/10/03)
The intramolecular cyclization of malonic acid allylic esters yields bicyclic cyclopropane carboxylic acid lactones in a phase transfer catalysed reaction. The substituents of the allylic moiety and the reaction temperature influence the diastereomeric composition of the products.
Synthesis of 4-Alkyl-2(5H)-furanones
Kametani, Tetsuji,Katoh, Tadashi,Tsubuki, Masayoshi,Honda, Toshio
, p. 61 - 66 (2007/10/02)
An alternative method for the synthesis of 4-alkyl-2(5H)-furanones is described.Intramolecular carbene addition reaction of α-diazo compounds (4) in the presence of rhodium acetate or copper acetylacetonate furnished the bicyclic compounds (5), which were subjected to cyclopropane ring-opening reaction to give the 4-alkyl-4,5-dihydrofuran-2(3H)-ones (6) regioselectively.These compounds (6) were further converted into 4-alkyl-2(5H)-furanones (14) in several steps.Keywords - carbene; intramolecular addition; butenolide; cyclopropanation; ring-opening reaction
