96567-95-2

Basic information

• Product Name: N-(3-methyl-3-pyrrolidinyl)acetamide
• CAS NO: 96567-95-2
• Molecular Weight: 142.201
• Mol File: 96567-95-2.mol

Chemical Properties

• CAS DataBase Reference: N-(3-methyl-3-pyrrolidinyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-methyl-3-pyrrolidinyl)acetamide(96567-95-2)
• EPA Substance Registry System: N-(3-methyl-3-pyrrolidinyl)acetamide(96567-95-2)

Safety Data

• Hazardous Substances Data: 96567-95-2(Hazardous Substances Data)

Upstream product

• 96567-93-0 1-benzyl-3-methylpyrrolidin-3-ol 
• 96567-94-1 N-(1-benzyl-3-methylpyrrolidin-3-yl)acetamide 

Relevant articles and documents

On the Ritter reaction of cyclic hydroxyamines: Synthesis of conformationally-restricted reduced amide dipeptide isosteres

The Ritter reactions of 3-alkyl-3-hydroxyazetidine or -piperidine derivatives give low yields of the desired products, whereas the 3-alkyl-3-hydroxy-pyrrolidine and 4-alkyl-4-hydroxy-piperidine derivatives react smoothly to give the corresponding acetamides. An alternative route to 3-acylamino-3-alkylpiperidines, which were designed as conformationally-restricted reduced amide dipeptide isosteres, was devised from nipecotic acid vai a Hofmann rearrangement.

Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives

The present invention relates to a 1,8-naphthyridine derivative of the formula STR1 wherein R1, R2 and R3 are the same or different and each hydrogen or lower alkyl having 1 to 5 carbon atoms; and esters thereof and salts thereof and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful antibacterial agents.