96567-94-1

Basic information

• Product Name: Acetamide, N-[3-methyl-1-(phenylmethyl)-3-pyrrolidinyl]-
• CAS NO: 96567-94-1
• Molecular Formula: C14H20N2O
• Molecular Weight: 232.326
• Mol File: 96567-94-1.mol

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[3-methyl-1-(phenylmethyl)-3-pyrrolidinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[3-methyl-1-(phenylmethyl)-3-pyrrolidinyl]-(96567-94-1)
• EPA Substance Registry System: Acetamide, N-[3-methyl-1-(phenylmethyl)-3-pyrrolidinyl]-(96567-94-1)

Safety Data

• Hazardous Substances Data: 96567-94-1(Hazardous Substances Data)

Upstream product

• 775-16-6 N-benzyl-3-pyrrolidinone 
• 75-05-8 acetonitrile 
• 96567-93-0 1-benzyl-3-methylpyrrolidin-3-ol 

Downstream Products

• 181114-75-0 1-Benzyl-3-(N-t-butoxycarbonylamino)-3-methylpyrrolidine 
• 147459-52-7 3-tert-butoxycarbonylamino-3-methyl-pyrrolidine 
• 181114-76-1 3-amino-1-benzyl-3-methylpyrrolidine 
• 96567-95-2 N-(3-methyl-3-pyrrolidinyl)acetamide 

Relevant articles and documents

CARBAMATE AND UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1

This invention relates to novel compounds of the Formula I, II, III, IHa, NIb, IV, IVa, IVb, IVc, IVd, IVe, V, Va, Vb1 Vl, Vla, VIb, VII, Vila, VIIb, VIII, Vllla, VIIIb, IX, IXa, X, and Xa, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11 β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell.

1-(HETERO)ARYL-3-AMINO-PYROLLIDINE DERIVATIVES FOR USE AS MGLUR3 RECEPTOR ANTAGONISTS

The present invention relates to compounds of the Formula (I) which are useful for treating conditions associated with mGluR3 receptors, such as depression, schizophrenia and migraine, pharmaceutical compositions thereof, and methods of using the same.

On the Ritter reaction of cyclic hydroxyamines: Synthesis of conformationally-restricted reduced amide dipeptide isosteres

The Ritter reactions of 3-alkyl-3-hydroxyazetidine or -piperidine derivatives give low yields of the desired products, whereas the 3-alkyl-3-hydroxy-pyrrolidine and 4-alkyl-4-hydroxy-piperidine derivatives react smoothly to give the corresponding acetamides. An alternative route to 3-acylamino-3-alkylpiperidines, which were designed as conformationally-restricted reduced amide dipeptide isosteres, was devised from nipecotic acid vai a Hofmann rearrangement.

Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives

The present invention relates to a 1,8-naphthyridine derivative of the formula STR1 wherein R1, R2 and R3 are the same or different and each hydrogen or lower alkyl having 1 to 5 carbon atoms; and esters thereof and salts thereof and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful antibacterial agents.