96603-36-0Relevant academic research and scientific papers
A radical-mediated 1,3,4-trifunctionalization cascade of 1,3-enynes with sulfinates andtert-butyl nitrite: facile access to sulfonyl isoxazoles
Yue, Xin,Hu, Ming,He, Xingyi,Wu, Shuang,Li, Jin-Heng
supporting information, p. 6253 - 6256 (2020/06/22)
An unprecedented indium-promoted three-component 1,3,4-trifunctionalization cascade of 1,3-enynes with sodium sulfinates andtert-butyl nitrite (TBN) to access 5-sulfonylisoxazolesvia[3+2] annulation is reported. By employing TBN as both the radical initiator and the N-O two atom unit, this method enables the formation of three new carbon-heteroatom bonds, C-S, C-N and C-O bonds, in a single reaction through a sequence of sulfonylation, isomerization, nitration and annulation with a broad substrate scope, excellent selectivity and the potential of late-stage functionalization of natural products.
THE 5-ALKOXYMETHYL-, 5-ALKYLTHIOMETHYL-, AND 5-DIALKYLAMINOMETHYL-ISOXAZOLES
Micetich, Ronald G.,Shaw, Chia C.,Hall, Tse W.,Spevak, Paul,Fortier, Robert A.,et al.
, p. 571 - 583 (2007/10/02)
A variety of methods were used for the preparation of the 5-alkoxymethyl-, 5-alkylthiomethyl,- and 5-dialkylaminomethyl-isoxazoles.A novel method for the separation of the isomeric mixture of 3-(5-)methoxymethyl-5-(3-)methylisoxazoles (obtained by the rea
