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Usage

Uses

Used in Automotive Paints and Coatings Industry:
CHEMPACIFIC 38143 is used as a solvent in automotive paints and coatings for its ability to provide excellent adhesion to various surfaces. This ensures that the paint remains intact and maintains its protective and aesthetic qualities over time.
CHEMPACIFIC 38143 is also used to enhance the gloss of automotive coatings, giving vehicles a shiny and attractive appearance that is desirable in the automotive industry.
Furthermore, this chemical mixture is utilized to improve the durability of automotive coatings, making them resistant to wear, weathering, and other environmental factors, thus prolonging the lifespan of the paint job.
It is crucial to handle CHEMPACIFIC 38143 with care, adhering to safety guidelines and regulations due to the volatile and potentially hazardous nature of its components.

InChI:InChI=1/C7H9NO/c1-6-5-8-4-3-7(6)9-2/h3-5H,1-2H3

Upstream product

• 67-56-1 methanol 
• 95680-54-9 4-azido-3-methylpyridine 
• 26883-29-4 4-methoxy-3-methylpyridine N-oxide 
• 1003-73-2 3-picoline-N-oxide 
• 1074-98-2 3-methyl-4-nitropyridine N-oxide 

Downstream Products

• 143798-69-0 1,3-dimethyl-4-pyridinone 
• 109341-81-3 4-methoxy-1,3-dimethylpyridinium iodide 
• 83575-92-2 5-methyl-2,4-diphenylpyridine 

Relevant academic research and scientific papers

Total synthesis of (±)-cylindrospermopsin

The first total synthesis of the novel hepatotoxin (±)- cylindrospermopson (1) has been accomplished in 20 steps from 4-methoxy-3- methylpyridine (12) in 3.5% overall yield. The substituted piperidine A ring 19 was generated stereospecifically by a four-step sequence using the addition of trimethylsilylethynylmagnesium bromide to 12 to give 16 and stereospecific addition of vinylcuprate to 16 to form 17. The reaction of diamine 26 with cyanogen bromide produced the cyclic guanidine C ring of 27. The key step in the synthesis was bromination of ketone 31, followed by hydrogenation to liberate the free guanidine, which underwent an intramolecular S(N)2 reaction to form the tetrahydropyrimidine ring B of 32. Further hydrogenation reduced the ketone to yield 42% of 32 containing the fully functionalized tricyclic system and protected hydroxymethyluracil side chain of cylindrospermopsin. Hydrolysis of the pyrimidine in concentrated hydrochloric acid and selective monosulfation completed the synthesis of cylindrospermopsin.

THERMOLYSIS OF 4-PYRIDYLAZIDES LEADING TO THE SYNTHESIS OF 6H-1,4-DIAZEPINES

Thermolysis of a methanolic solution of 4-pyridylazides (1) at 200 deg C for 8-12 min was found to give unstable but isolable 5-methoxy-6H-1,4-diazepines (4) and (5), along with 32-45percent yield of 5,6-dihydro-6-methoxy-7H-tetrazolodiazepines (6)