96689-89-3

Upstream product

• 16838-89-4 2,3,5-tri-O-benzyl-D-ribofuranose 
• 621-23-8 1,2,3-trimethoxybenzene 
• 213202-76-7 Methanesulfonic acid (3R,4R,5R)-3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl ester 

Downstream Products

• 29161-71-5 β-1-deoxy-1-(C-2',4',6'-trimethoxyphenyl)-D-ribofuranose 

Relevant academic research and scientific papers

Surfactant-type Bronsted acid catalyzed dehydrative nucleophilic substitutions of alcohols in water

(Chemical Equation Presented) A protocol for the dehydrative nucleophilic substitution of benzyl alcohols with a variety of carbon- and heteroatom-centered nucleophiles using dodecylbenzenesulfonic acid (DBSA) as a surfactant-type Bronsted acid catalyst i

Application of the versatile character of the tellurium atom for the synthesis of C-nucleoside analogues via sugar tellurides

Making use of the versatile character of the tellurium atom such as its radicophilicity, nucleophilicity and electrophilicity, D-ribofuranosyl, 2-deoxy-D-ribofuranosyl and D-glucosyl p-methoxyphenyl tellurides have been prepared. Under suitable conditions, the corresponding anomeric radical, anomeric cation and anomeric anion, respectively, are formed from the sugar tellurides. By the following coupling reactions of the anomeric radical and anomeric cation to electron-poor and electron-rich aromatics, respectively, the corresponding C-nucleoside analogues have been synthesized in moderate yields. The anomeric anion has also been trapped by an electrophile such as benzaldehyde.

Strategic approach to C-nucleosides via sugar anomeric radical, cation, and anion with sugar tellurides

Direct coupling reactions of the protected D-ribofuranosyl p-anisyl telluride and 2-deoxy-D-ribofuranosyl p-anisyl telluride with electron-poor heteroaromatics and electron-rich aromatics via anomeric radical, cation, and anion were carried out.

An efficient glycosylation reaction of 1-hydroxy sugars with various nucleophiles using a catalytic amount of activator and hexamethyldisiloxane

In the presence of hexamethyldisiloxane and anhydrous calcium sulfate, a catalytic amount of activator such as tin(II) trifluoromethanesulfonate, ytterbium trifluoromethanesulfonate, lanthanum trifluoromethanesulfonate or tin(II) chloride smoothly promote