96736-00-4

Basic information

• Product Name: 4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID
• Synonyms: BOC-4-HYDRAZINOBENZOIC ACID;BOC-NH-ABZ(4)-OH;4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID;4-(BOC-HYDRAZINO)-BENZOIC ACID;4-(N'-BOC-HYDRAZINO)-BENZOIC ACID;4-(T-BUTOXYCARBONYL-HYDRAZINO)-BENZOIC ACID;4-(2-(tert-Butoxycarbonyl)hydrazinyl)benzoic acid;4-[2-(tert-Butoxycarbonyl)hydrazino]benzoic acid
• CAS NO: 96736-00-4
• Molecular Formula: C₁₂H₁₆N₂O₄
• Molecular Weight: 252.27
• Mol File: 96736-00-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID(96736-00-4)
• EPA Substance Registry System: 4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID(96736-00-4)

Safety Data

• Hazardous Substances Data: 96736-00-4(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 619-67-0 4-Hydrazinobenzoic acid 
• 24589-77-3 4-hydrazinobenzoic acid hydrochloride 

Downstream Products

• 848083-52-3 (4-{[(tert-butoxy)carbonylamino]amino}phenyl)-N-{2-[(phenylmethoxy)carbonylamino]ethyl}carboxamide 
• 852286-99-8 N'-[4-(1,2,2,6,6-pentamethyl-piperidin-4-yl-carbamoyl)-phenyl]-hydrazinecarboxylic acid ter-butyl ester 
• 848083-51-2 C₂₈H₃₄N₈O₆S 
• 848083-55-6 (2S)-N-({4-[N-(2-aminoethyl)carbamoyl]phenyl}amino)-2-[(tert-butoxy)carbonylamino]-4-methylpentanamide 

Relevant articles and documents

Hydrogen peroxide based oxidation of hydrazines using HBr catalyst

Azo compounds (RN = NR′) are an important class of organic molecules that find wide application in organic synthesis. Herein, we report an efficient, practical and metal-free oxidation of hydrazines (RNH-NHR’) to azo compounds using 5 mol% HBr and hydrogen peroxide as terminal oxidant. This new method has been demonstrated by 40 examples with excellent yields. In addition, we showcased two examples of the one-pot sequential reactions involving our hydrazine oxidation/hydrolysis/Heck reaction or Cu-catalyzed N-arylation with aryl boronic acid. The distinct advantages of this protocol include metal-free catalysis, waste prevention, and easy operation.

3,5-BIS(PHENYL)-1H-HETEROARYL DERIVATIVES AS MEDICAMENTS

The present invention claims compounds of general formula I: wherein the meaning of individual substituents is described in the claims. The compounds are useful in treatment of cancers, due to their multi-modal mechanism of action.

NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP

The present invention relates to compounds of azapeptide or azapeptidomimetic type of formula (I): in which R1, R2, R3, X1, X2, X3, X4 and Y are as defined in claim 1, to pharmaceutical compositions containing them and to such compounds as adjuvant for an anticancer or anti-infectious medicament.