96758-64-4Relevant academic research and scientific papers
A facile synthesis of 5-substituted 2-furylacetates via 6-hydroxy-3-oxo-4-hexenoates
Kawano, Tomikazu,Ogawa, Toru,Islam, Saiful Md.,Ueda, Ikuo
, p. 7685 - 7688 (2007/10/02)
6-Substituted 3-ethoxy-6-hydroxy-2,4-hexadenoates (4) which were prepared by reaction of ethyl (4E)-3-ethoxy-5-formyl-2,4-pentadienoate (3a) with nucleophiles or sodium borohydride reduction of 6-substituted 3-ethoxy-6-oxo-2,4-hexadenoates (3b-e) have been converted in very good yields into 5-substituted 2-furylacetates (5) by treating with 47% HBr in THF.
Additions of 1,1-Diethoxyethene to 1,2-Diketones
Mattay, Jochen,Runsink, Jan
, p. 2815 - 2818 (2007/10/02)
The ketene acetal 2 undergoes thermally noncatalyzed additions to various 1,2-diketones under formation of - and -adducts.Only with biacetyl 1a could an oxetane, 3, be isolated whereas mainly substituted 6-oxo-2,4-hexadienoic acid ethyl esters 6 and 7 are formed with aromatic 1,2-diketones.The regioselectivities and the product ratios are discussed in terms of a mechanism via zwitterionic intermediates.
