96783-85-6

Basic information

• Product Name: 2-Fluoro-6-MethylaMino-benzonitrile
• Synonyms: 2-Fluoro-6-MethylaMino-benzonitrile;Benzonitrile, 2-fluoro-6-(MethylaMino)-
• CAS NO: 96783-85-6
• Molecular Formula: C8H7FN2
• Molecular Weight: 150.1529832
• EINECS: -0
• Mol File: 96783-85-6.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 2-Fluoro-6-MethylaMino-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-6-MethylaMino-benzonitrile(96783-85-6)
• EPA Substance Registry System: 2-Fluoro-6-MethylaMino-benzonitrile(96783-85-6)

Safety Data

• Hazardous Substances Data: 96783-85-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Fluoro-6-MethylaMino-benzonitrile is used as a synthetic intermediate for the production of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new medications, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Fluoro-6-MethylaMino-benzonitrile is utilized as a precursor in the synthesis of agrochemicals. Its application aids in the creation of effective compounds for pest control and crop protection, thereby supporting agricultural productivity and food security.
As a Building Block in Medicinal Chemistry:
2-Fluoro-6-MethylaMino-benzonitrile is used as a structural component in medicinal chemistry for designing and developing innovative drug candidates. Its presence in these candidates can potentially enhance the pharmacological properties and therapeutic effects of new medications.

Upstream product

• 1897-52-5 2,6 difluorobenzonitrile 
• 74-89-5 methylamine 
• 77326-36-4 2-amino-6-fluorobenzonitrile 

Relevant articles and documents

Metal-Free Organoselenium-Enabled Radical Relay Azidation-Carbocyclization

An organoselenium-enabled radical relay Azidation-carbocyclization reaction for the preparation of azide-substituted quinoline-2,4-diones was developed. A series of previously unknown structurally diverse azide- substituted quinoline-2,4-diones were obtai

Pharmaceutically active compounds

Compounds of formula (I) wherein: R1 and R19 independently represent hydrogen, alkyl C1-6, alkoxy C1-6, alkylthio C1-6, halogen, hydroxyl or amino; R2 represents H or alkyl; R3 represents phenyl, a 6-membered heterocyclic aromatic ring containing one or two nitrogen atoms, or a 5-membered heterocyclic aromatic ring containing 1 to 3 heteroatoms selected from O,N, and S, which phenyl or heterocyclic aromatic ring may be optionally substituted by alkyl C1-6, alkoxy C1-6, haologen, hydroxyl, alkylthio C1-6, cyano, trifluoromethyl, nitro, hydroxymethyl, amino, a group --(CH2)c NHCO2 R10, a group --(CH2)c NR5 R6, or a group --CO2 R11 ; or R3 represents hydrogen or alkyl C1-8, which alkyl group may be optionally substituted by amino or a group --NHCO2 R10 ; R4 represents hydrogen or alkyl C1-6; or R3 and R4 taken together represent a group (CH2)a Z(CH2)b ; c represents an integer 0 to 2; and pharmaceutically acceptable salts thereof, have been found to be useful as a pharmaceuticals. The compounds may especially be used in the treatment of inflammatory disorders.

Process for the production of 2,6-diaminobenzonitrile derivatives

2,6-Diaminobenzonitriles, useful in the production of N-(2-cyano-3-substituted or unsubstituted amino-phenyl)oxamate and N-(2-cyano-3-substituted or unsubstituted amino-phenyl)tetrazole-5-carboxamide antiallergy and antisecretory agents, are prepared by sequential displacement of the fluoro substituents from 2,6-difluorobenzonitrile with the appropriately substituted amine.