96789-87-6

Usage

Molecular structure

The compound consists of a toluene group attached to a hexanoic acid chain through a sulfonamido linkage.

Usage

Commonly used in the production of pharmaceuticals and as an intermediate in organic synthesis.

Potential applications

Can be used as a building block for the synthesis of various pharmaceutical drugs.

Properties

Possesses properties that make it suitable for use as a precursor in the production of certain drugs.

Structure

Allows for further modification and functionalization to tailor its properties to specific applications.

Value

The precise structure and properties make it a valuable tool in the development of new pharmaceutical products.

Upstream product

• 616-06-8 2-amino-hexanoic acid 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 500726-34-1 2-(toluene-4-sulfonamido)hexan-1-ol 
• 51220-83-8 methyl 2-((4-methylphenyl)sulfonamido)hexanoate 
• 863403-33-2 (E)-carbonic acid methyl ester 4-{(4-methylbenzyl)-[2-(toluene-4-sulfonyl)acetyl]amino}oct-2-enyl ester 
• 863403-30-9 (E)-4-{(4-methylbenzyl)[2-(toluene-4-sulfonyl)acetyl]amino}oct-2-enol 
• 863403-21-8 (E)-ethyl (toluene-4-sulfonamido)oct-2-enoate 
• 863403-24-1 (E)-4-(toluene-4-sulfonamido)oct-2-en-1-ol 
• 863403-27-4 (E)-4-(4-methylbenzylamino)oct-2-en-1-ol 
• 854265-60-4 N-(1-formyl-pentyl)-4-methyl-benzenesulfonamide 

Relevant academic research and scientific papers

Stereoselective γ-lactam synthesis via palladium-catalysed intramolecular allylation

A novel route to the synthesis of 3-(tolylsulfonyl)-4,5-cis-disubstituted γ-lactams using a diastereoselective palladium-catalysed intramolecular allylation of amino acid-derived allylic carbonates has been developed. The Royal Society of Chemistry 2005.

Triiodide-Mediated δ-Amination of Secondary C?H Bonds

The Cδ?H amination of unactivated, secondary C?H bonds to form a broad range of functionalized pyrrolidines has been developed by a triiodide (I3?)-mediated strategy. By in situ 1) oxidation of sodium iodide and 2) sequestration of the transiently generated iodine (I2) as I3?, this approach precludes undesired I2-mediated decomposition which can otherwise limit synthetic utility to only weak C(sp3)?H bonds. The mechanism of this triiodide-mediated cyclization of unbiased, secondary C(sp3)?H bonds, by either thermal or photolytic initiation, is supported by NMR and UV/Vis data, as well as intercepted intermediates.