51220-83-8Relevant academic research and scientific papers
Triiodide-Mediated δ-Amination of Secondary C?H Bonds
Wappes, Ethan A.,Fosu, Stacy C.,Chopko, Trevor C.,Nagib, David A.
, p. 9974 - 9978 (2016/08/16)
The Cδ?H amination of unactivated, secondary C?H bonds to form a broad range of functionalized pyrrolidines has been developed by a triiodide (I3?)-mediated strategy. By in situ 1) oxidation of sodium iodide and 2) sequestration of the transiently generated iodine (I2) as I3?, this approach precludes undesired I2-mediated decomposition which can otherwise limit synthetic utility to only weak C(sp3)?H bonds. The mechanism of this triiodide-mediated cyclization of unbiased, secondary C(sp3)?H bonds, by either thermal or photolytic initiation, is supported by NMR and UV/Vis data, as well as intercepted intermediates.
Development of the copper-catalyzed olefin aziridination reaction
Evans, David A.,Faul, Margaret M.,Bilodeau, Mark T.
, p. 2742 - 2753 (2007/10/02)
Soluble Cu(I) and Cu(II) triflate and perchlorate salts are efficient catalysts for the aziridination of olefins employing (N-(p-tolylsulfonyl)imino)phenyliodinane, PhI=NTs, as the nitrene precursor. Electron-rich as well as electron-deficient olefins und
LES ORGANOCUPRATES DANS UNE NOUVELLE SYNTHESE D'AMINOACIDES ENANTIOMERIQUEMENT PURS
Bajgrowicz, J. A.,Hallaoui, A. El,Jacquier, R.,Pigiere, Ch.,Viallefont, Ph.
, p. 1833 - 1845 (2007/10/02)
A new general method of synthesis of optically pure α- amino esters was elaborated during studies on the reaction of organocuprates with tosyl and halogeno derivatives of L-serine and L-homoserine.
LITHIUM DIORGANOCUPRATE REACTIONS WITH L-SERINE DERIVATIVES
Bajgrowicz, J. A.,Hallaoui, A. El,Jacquier, R.,Pigiere, Ch.,Viallefont, Ph.
, p. 2759 - 2762 (2007/10/02)
The lithium diorganocuprate reactions with L-serine derivatives are studied.Retention of configuration, or at least a high enantiomeric excess (> 80percent) of the formed α-amino esters is observed in all cases.Attempts are made to restrict side-reactions.
UTILISATION DES ORGANOCUPRATES A LA SYNTHESE D'AMINOACIDES
Bernardini, A.,Hallaoui, A. El,Jacquier, R.,Pigiere, Ch.,Viallefont, Ph.,Bajgrowicz, J.
, p. 3717 - 3720 (2007/10/02)
The reaction of the organocuprate R2CuLi with iodo, bromo or tosyl amino acids gives excellent yields of the substitution products without affecting the configuration of amino acids.
