96799-03-0

Basic information

• Product Name: 5-Thien-2-yl-1H-pyrazol-3-amine
• Synonyms: 3-(2-Thienyl)-1H-pyrazole-5-amine;5-Amino-3-(2-thienyl)-1H-pyrazole;5-(thiophen-2-yl)-1H-pyrazol-3-aMine;5-(Thien-2-yl)-2H-pyrazol-3-ylaMine;5-Amino-3-(2-thienyl)pyrazole 96%;TIMTEC-BB SBB005504;BUTTPARK 30\03-81;5-THIEN-2-YL-1H-PYRAZOL-3-AMINE
• CAS NO: 96799-03-0
• Molecular Formula: C₇H₇N₃S
• Molecular Weight: 165.22
• Product Categories: Heterocyclic Compounds;Heterocycles;C7 and C8;Heterocyclic Building Blocks;Pyridines;Amines;Sulfur & Selenium Compounds
• Mol File: 96799-03-0.mol

Chemical Properties

• Melting Point: 101-103°C
• Boiling Point: 453.8 °C at 760 mmHg
• Flash Point: 228.2 °C
• Appearance: yellow solid
• Density: 1.4 g/cm³
• Vapor Pressure: 2.02E-08mmHg at 25°C
• Refractive Index: 1.707
• Storage Temp.: 2-8°C(protect from light)
• Solubility: DMSO, Methanol
• BRN: 4399374
• CAS DataBase Reference: 5-Thien-2-yl-1H-pyrazol-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thien-2-yl-1H-pyrazol-3-amine(96799-03-0)
• EPA Substance Registry System: 5-Thien-2-yl-1H-pyrazol-3-amine(96799-03-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• Hazardous Substances Data: 96799-03-0(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Solid

InChI:InChI=1/C7H7N3S/c8-7-4-5(9-10-7)6-2-1-3-11-6/h1-4H,(H3,8,9,10)

Upstream product

• 33898-90-7 2-Thenoylacetonitrile 
• 98-03-3 thiophene-2-carbaldehyde 
• 545-06-2 trichloroacetonitrile 

Downstream Products

• 1403500-26-4 8-(piperazin-1-yl)-1-(thiophen-2-yl)-5-(2,3,6-trifluorophenyl)indeno[1,2-d]pyrazolo[3,4-b]pyridin-6(3H)-one 
• 1403501-16-5 ethyl 4-(4-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenyl)-3-(thiophen-2-yl)-6-(2,3,6-trifluorophenyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate 
• 1426138-00-2 C₁₉H₂₁N₅OS₂ 
• 1426137-99-6 C₂₀H₁₇N₅OS₂ 
• 1426137-98-5 C₁₉H₁₄N₆O₃S₂ 
• 1426137-97-4 C₁₉H₁₅N₅OS₂ 
• 1426137-91-8 1-(2-thenoyl)-3-(2-thienyl-1H-pyrazol-5-yl)-2-(N-p-tolyl)guanidine 
• 1403501-15-4 ethyl 4-(4-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenyl)-3-(thiophen-2-yl)-6-(2,3,6-trifluorophenyl)-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylate 
• 1195784-85-0 C₁₆H₁₂N₄S 
• 1001091-04-8 4-(3-(thiophen-2-yl)-5-oxo-1,4,10-trihydro-5H-indeno[1,2-b]pyrazolo[4,3-e]pyridin-4-yl)benzonitrile 
• 1022926-60-8 C₁₉H₁₄N₄O₂S 

Relevant articles and documents

Synthesis of pyrazolopyrimidinones using a “one-pot” approach under microwave irradiation

A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established. A variety of substituents was tolerated at the 2 and 5 positions, including functionalized aryls, heterocycles, and alkyl groups.

New synthesis of 3-aryl-5-amino-1H-pyrazoles

A new efficient procedure has been proposed for the synthesis of 3-aryl-5-amino-1H-pyrazoles by reaction of α-chloro-β- arylacrylonitriles with hydrazine hydrate.