96839-05-3Relevant academic research and scientific papers
Imino Diels-Alder Reaction of 2-t-Butyldimethylsilyloxycyclohexadiene: Isolation of an Azabicyclooctene Silyl Enol Ether Adduct
Birkinshaw, Timothy N.,Tabor, Alethea B.,Holmes, Andrew B.,Raithby, Paul R.
, p. 1601 - 1602 (2007/10/02)
The imino Diels-Alder reaction of (1) with 2-t-butyldimethylsilyloxycyclohexadiene (2) gave after acidic work-up mainly the bicyclic enol ethers (5a) (for which a novel X-ray crystal structure determination is reported) and (5b) together with small amounts of bicyclic ketones (3a,b) and cyclohexenones (4a,b).
The Products of an Imino Diels-Alder Reaction with 2-Trimethylsilyloxycyclohexadiene: Synthesis, X-Ray Crystal Structures, and Mechanistic Implications
Birkinshaw, Timothy N.,Tabor, Alethea B.,Holmes, Andrew B.,Kaye, Perry,Mayne, Peter M.,Raithby, Paul R.
, p. 1599 - 1601 (2007/10/02)
The reaction of the N-tosyl imino-ester (1) with 2-trimethylsilyloxycyclohexadiene (2) followed by acidic work-up shows a divergence in pathways: at low temperature in polar solvents the cyclohexenones (5) and (6) (X-ray) are favoured, whereas at higher temperatures the bicyclic ketones (3) and (4) (X-ray) are the predominant products.
Total Synthesis of (+/-)-Isoprosopinine B and (+/-)-Desoxoprosopinine
Holmes, Andrew B.,Thompson, John,Baxter, Andrew J. G.,Dixon, John
, p. 37 - 39 (2007/10/02)
The synthesis of the title compounds (10) and (16) in eleven and ten steps respectively from the imine (1) and 2-trimethylsilyloxycyclohexa-1,3-diene (2) via the azabicyclo-octanone (3) and the triol (5) illustartes a new general method for the preparation of the prosopis alkaloids.
