96850-73-6

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 513-31-5 2-bromoallyl bromide 

Downstream Products

• 1070895-95-2 1-(4-methoxybenzyl)-2-methylideneaziridine 
• 1437300-31-6 4-(hex-4-yn-1-yl)-1-(4-methoxybenzyl)-2,3-dimethyl-1H-pyrrole 
• 1437300-27-0 dimethyl 2-(but-2-yn-1-yl)-2-((1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrol-3-yl)methyl)malonate 

Relevant academic research and scientific papers

Nickel-catalyzed [3 + 2] cycloaddition of diynes with methyleneaziridines via C-C bond cleavage

A Ni-catalyzed [3 + 2] cycloaddition via C-C bond cleavage of methyleneaziridines under mild conditions was developed. This reaction gave substituted pyrroles with excellent regioselectivity and a pendant alkyne unit, which is advantageous for further derivatization. The Royal Society of Chemistry 2013.

Rapid synthesis of 1,3,4,4-tetrasubstituted β-lactams from methyleneaziridines using a four-component reaction

(Chemical Equation Presented) 2-Methyleneaziridines can be transformed into a variety of 1,3,4,4-tetrasubstituted β-lactams in moderate to good yields (46-63%) via a one-pot process that brings together four components with the formation of three new intermolecular carbon-carbon bonds.