1070895-95-2

Basic information

• Product Name: 1-(4-methoxybenzyl)-2-methylideneaziridine
• Synonyms: 1-(4-methoxybenzyl)-2-methylideneaziridine
• CAS NO: 1070895-95-2
• Molecular Weight: 175.23
• Mol File: 1070895-95-2.mol

Chemical Properties

• CAS DataBase Reference: 1-(4-methoxybenzyl)-2-methylideneaziridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxybenzyl)-2-methylideneaziridine(1070895-95-2)
• EPA Substance Registry System: 1-(4-methoxybenzyl)-2-methylideneaziridine(1070895-95-2)

Safety Data

• Hazardous Substances Data: 1070895-95-2(Hazardous Substances Data)

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 96850-73-6 (2-bromoallyl)-(4-methoxybenzyl)-amine 

Downstream Products

• 1070896-23-9 3-benzyloxy-1-(4-methoxy-benzyl)-4-pentyl-4-(2-phenylethyl)-azetidin-2-one 
• 1070896-02-4 C₃₄H₃₅NO₃ 
• 1437300-27-0 dimethyl 2-(but-2-yn-1-yl)-2-((1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrol-3-yl)methyl)malonate 
• 1437300-31-6 4-(hex-4-yn-1-yl)-1-(4-methoxybenzyl)-2,3-dimethyl-1H-pyrrole 
• 1589546-33-7 C₂₆H₃₀N₂O₃S 
• 1589546-48-4 C₂₆H₃₀N₂O₃S 

Relevant articles and documents

Nickel-catalyzed [3 + 2] cycloaddition of diynes with methyleneaziridines via C-C bond cleavage

A Ni-catalyzed [3 + 2] cycloaddition via C-C bond cleavage of methyleneaziridines under mild conditions was developed. This reaction gave substituted pyrroles with excellent regioselectivity and a pendant alkyne unit, which is advantageous for further derivatization. The Royal Society of Chemistry 2013.

Rapid synthesis of 1,3,4,4-tetrasubstituted β-lactams from methyleneaziridines using a four-component reaction

(Chemical Equation Presented) 2-Methyleneaziridines can be transformed into a variety of 1,3,4,4-tetrasubstituted β-lactams in moderate to good yields (46-63%) via a one-pot process that brings together four components with the formation of three new intermolecular carbon-carbon bonds.