96917-15-6

Basic information

• Product Name: (E)-2-(4'-benzyloxy-3'-methoxybenzylidene)succinic acid
• Synonyms: (E)-2-(4'-benzyloxy-3'-methoxybenzylidene)succinic acid
• CAS NO: 96917-15-6
• Molecular Weight: 342.348
• Mol File: 96917-15-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (E)-2-(4'-benzyloxy-3'-methoxybenzylidene)succinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4'-benzyloxy-3'-methoxybenzylidene)succinic acid(96917-15-6)
• EPA Substance Registry System: (E)-2-(4'-benzyloxy-3'-methoxybenzylidene)succinic acid(96917-15-6)

Safety Data

• Hazardous Substances Data: 96917-15-6(Hazardous Substances Data)

Upstream product

• 1391062-42-2 C₂₁H₂₂O₆ 
• 100-44-7 benzyl chloride 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 121-33-5 vanillin 
• 100-39-0 benzyl bromide 
• 123-25-1 succinic acid diethyl ester 

Downstream Products

• 1275548-13-4 4,4',4'',4'''-tetrabenzyloxy-cannabisin G 
• 888483-54-3 trans-(E)-2,3-bis(4'-benzyloxy-3'-methoxybenzylidene)succinic acid 
• 1243054-20-7 trans-(E)-dimethyl 2,3-bis(4'-benzyloxy-3'-methoxybenzylidene)succinic acid 
• 1243054-22-9 trans-(E)-dimethyl 2,3-bis(4-benzyloxy-3-methoxybenzylidene)-1,4-butanediol 
• 57759-55-4 (2R,3R)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediol 
• 3688-23-1 2,3-Bis(3-methoxy-4-hydroxybenzyl)butane-1,4-diol 
• 99055-08-0 (S)-3-(4-Benzyloxy-3-methoxy-benzyl)-dihydro-furan-2-one 
• 99055-08-0 (R)-3-(4-Benzyloxy-3-methoxy-benzyl)-dihydro-furan-2-one 
• 124988-58-5 (S)-4-<<4-(benzyloxy)-3-methoxyphenyl>methyl>dihydro-2(3H)-furanone 
• 111266-03-6 (R)-(+)-3-(4-benzyloxy-3-methoxybenzyl)-γ-butyrolactone 
• 129339-93-1 (S)-(-)-2-(4-benzyloxy-3-methoxybenzyl)butane-1,4-diol 
• 129339-88-4 (R)-2-(4-Benzyloxy-3-methoxy-benzyl)-butane-1,4-diol 
• 201742-42-9 2-[1-(3,4-Dimethoxy-phenyl)-meth-(Z)-ylidene]-3-[1-(4-hydroxy-3-methoxy-phenyl)-meth-(Z)-ylidene]-succinic acid dimethyl ester 

Relevant articles and documents

Total synthesis of (±)-agastinol

A synthesis of the tetrahydrofuran lignan (±)-agastinol, starting from the cheap Vanillin, has been developed based on Stobbe reaction with diethyl succinate to give the skeleton of lignan, which was then reduced to afford meso- and threo-(±)-secoisolanciresinol. threo-(±)- Secoisolanciresinol was treated with DDQ in acetic acid to give the 2-aryl tetrahydrofuran lignan, and which was then condensed with ferulic acid to give (±)-agastinol for the first time.

Synthesis of threo-(±)-9,9-dibenzoylsecoisolariciresinol and its isomer

The total synthesis of threo-(±)-9,9-dibenzoylsecoisolariciresinol and its isomer based on two Stobbe reactions as C-C bond-forming steps used a protected vanillin and diethyl; succinate to give the skeleton of lignan, followed by reduction to afford threo-and meso-(±)-secoisolariciresinol Both were treated with benzoyl chloride to obtain the natural product threo-(±)-9,9-dibenzoylsecoisolariciresinol and Its isomer meso-(±)-9,9-dibenzoylsecoisolariciresinol for the first time.

LIGNAN FROM CALYCES OF DIOSPYROS KAKI

Key Word Index - Diospyros kaki; Ebenaceae; calyx; (-)-divanillyltetrahydrofuran ferulate. - From Diospyros kaki calyces, a new lignan was isolated.Its structure was elucidated as (-)-divanyllyltetrahydrofuran ferulate by spectroscopic methods and was established by total synthesis.