96928-30-2 Usage
Main Properties of Fenbufen
1. Chemical Structure: 2-[4-[2-[(4-chlorophenyl)amino]-1,3-thiazol-4-yl]phenoxy]propanoic acid.
2. Classification: Nonsteroidal anti-inflammatory drug (NSAID).
3. Mechanism of Action: Inhibits the production of prostaglandins, reducing inflammation and pain.
4. Route of Administration: Typically administered orally.
5. Forms Available: Tablets, capsules, and oral suspensions.
Usage
Pain-relieving and anti-inflammatory properties.
Conditions Treated
Rheumatoid arthritis, osteoarthritis, musculoskeletal pain.
Side Effects
Gastrointestinal irritation, kidney damage, increased risk of cardiovascular events (with long-term use).
Caution
Should be used under the guidance of a healthcare professional due to potential side effects and risks associated with long-term use.
This information outlines the main properties and specific content related to fenbufen, providing a comprehensive understanding of its chemical nature, therapeutic uses, administration, and associated risks.
Check Digit Verification of cas no
The CAS Registry Mumber 96928-30-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,9,2 and 8 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 96928-30:
(7*9)+(6*6)+(5*9)+(4*2)+(3*8)+(2*3)+(1*0)=182
182 % 10 = 2
So 96928-30-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H15ClN2O3S/c1-11(17(22)23)24-15-8-2-12(3-9-15)16-10-25-18(21-16)20-14-6-4-13(19)5-7-14/h2-11H,1H3,(H,20,21)(H,22,23)
96928-30-2Relevant academic research and scientific papers
Synthesis and Mass Spectral Studies of Some Thiazolylphenoxypropionic Acids and Esters
Singh, S. P.,Vaid, R. K.,Bathla, Kamla
, p. 119 - 123 (2007/10/02)
Several 2- and 3-propionic acids (III and IV) have been prepared by the reaction of the corresponding phenacyl bromides with thioureas and thioamides (Hantzsch synthesis).The mass spectra of the esters (II) of III show a unique fragmentation resulting in the concerted loss of CH3CHO and CH3CH=C=O from the molecular ion through a rearrangement involving transfer of a hydrogen atom from ethyl group to the phenoxy oxygen.Another hydrogen transfer reaction leads to the concerted loss of CO2 and C2H4 from the molecular ion of IV.However, no such process is observed in the mass spectra of III.The thiazole ring suffers cleavage in a characteristic manner after the removal of acid/ester function in II, III and IV.The compounds have been screened for their antiinflammatory activity.
