96938-01-1Relevant academic research and scientific papers
Asymmetric Synthesis of (-) (R) Yashabushiketol
Solladie, Guy,Ziani-Cherif, Chewki,Jesser, Francis
, p. 931 - 934 (2007/10/02)
(-)(R) Yashabushiketol was prepared from the epoxide 4 readily available in both configurations by reduction of β-ketosulfoxides.
REDUCTION OF β-HYDROXYSULFOXIDES: APPLICATION TO THE SYNTHESIS OF OPTICALLY ACTIVE EPOXIDES
Solladie, Guy,Demailly, Gilles,Greck, Christine
, p. 435 - 438 (2007/10/02)
β-hydroxysulfoxides of opposite stereochemistry can be prepared in very high diastereoisomeric excesses (90 to 95 percent) by reduction of β-ketosulfoxides with DIBAL or DIBAL/ZnCl2.A very efficient method to transform these reduction products into optically active epoxides is also described.
