96994-73-9

Usage

Uses

Due to the limited information provided, the specific applications of 2-Dimethylamino-6-Fluorobenzonitrile cannot be accurately listed. However, based on its chemical structure and functional groups, it may have potential uses in various industries, such as:
Used in Pharmaceutical Industry:
2-Dimethylamino-6-Fluorobenzonitrile could be used as an intermediate in the synthesis of pharmaceutical compounds, given its aromatic and nitrile functional groups, which can be further modified or reacted to form bioactive molecules.
Used in Chemical Synthesis:
As an organic compound with a unique structure, 2-Dimethylamino-6-Fluorobenzonitrile may be utilized in the synthesis of other organic compounds, potentially serving as a building block or a precursor in various chemical reactions.
Used in Material Science:
2-DIMETHYLAMINO-6-FLUOROBENZONITRILE's aromatic and nitrile groups, along with the presence of a fluorine atom, may contribute to specific properties that could be exploited in the development of new materials with unique characteristics, such as improved stability or reactivity.

InChI:InChI=1/C9H9FN2/c1-12(2)9-5-3-4-8(10)7(9)6-11/h3-5H,1-2H3

Upstream product

• 1897-52-5 2,6 difluorobenzonitrile 
• 506-59-2 N,N-dimethylammonium chloride 
• 124-40-3 dimethyl amine 
• 680-31-9 N,N,N,N,N,N-hexamethylphosphoric triamide 

Downstream Products

• 335640-45-4 N-methyl-6-(dimethylamino)anthranilic acid 
• 335640-44-3 2-(dimethylamino)-6-methylaminobenzonitrile 

Relevant academic research and scientific papers

Discovery and optimization of 2,4-diaminoquinazoline derivatives as a new class of potent dengue virus inhibitors

The results of a high-throughput screening assay using the DENV-2 replicon showed that the 2,4-diaminoquinazoline derivative 4a has a high dengue virus inhibitory activity (EC50 = 0.15 μM). A series of 2,4-diaminoquinazoline derivatives based on 4a as a lead compound were synthesized and subjected to structure-antidengue activity relationship studies. Among the series of 2,4-diaminoquinazoline derivative probed, 4o was observed to display both the highest antiviral potency (EC50 = 2.8 nM, SI > 1000) and an excellent pharmacokinetic profile.

Synthesis and Biological Evaluation of New 1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for Treatment of Autoimmune Disorders: Structure-Activity Relationship

Roquinimex-related 3-quinolinecarboxamide derivatives were prepared and evaluated for treatment of autoimmune disorders. The compounds were tested in mice for their inhibitory effects on disease development in the acute experimental autoimmune encephalomyelitis model and selected compounds in the beagle dog for induction of proinflammatory reaction. Structure-activity relationships are discussed. Compound 8c, laquinimod, showed improved potency and superior toxicological profile compared to the lead compound roquinimex (1b, Linomide) and was selected for clinical studies (currently in phase II).

THE REACTION OF ACTIVATED ARYL AND HETEROARYL DIHALIDES WITH HMPA. A REGIOSELECTIVITY STUDY

A series of activated aryl and heteroaryl dihalides were reacted with HMPA at elevated temperatures.Of the eleven examples studied, all but one reacted in a regioselective manner to give a monohalo-N,N-dimethylamino derivative.