96997-17-0Relevant academic research and scientific papers
Substituted 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]decan-4-ones and 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]dec-2-en-4-ones
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, (2008/06/13)
This invention relates to 5-(substituted phenyl)-5-[(substituted amino)alkyl]-1,3-diazabicyclo[4.4.0]decan-4-ones and 5-(substituted phenyl)-5-[(substituted amino)-alkyl]-1,3-diazabicyclo[4.4.0]dec-2-en-4-ones that are useful as antiarrhythmic agents.
Synthesis and Structure-Activity Relationships of a New Series of Antiarrhytmic Agents: 4,4-Disubstituted Hexahydro-3H-pyridopyrimidin-3-ones and Related Compounds
Chorvat, Robert J.,Prodan, Kathleen A.,Adelstein, Gilbert W.,Rydzewski, Robert M.,McLauglin, Kathleen T.,et al.
, p. 1285 - 1291 (2007/10/02)
A series of 4,4-disubstituted tetrahydro- and 4,4-disubstituted hexahydro-3H-pyridopyrimidin-3-ones (4 and 5, respectively) were prepared from 2-aryl-2-(2-piperidinyl)-4-butanamides (2).Individual racemates of the piper
