97-35-8

Usage

Uses

Used in Cosmetics Industry:
Fast Red ITR is used as a colorant in cosmetics for its vibrant red hue and non-toxic properties, ensuring safety for use in personal care products.
Used in Plastics Industry:
In the plastics industry, Fast Red ITR is utilized as a pigment to impart a consistent and long-lasting red color to plastic materials, taking advantage of its high color strength and light fastness.
Used in Textile Industry:
Fast Red ITR is employed as a dye in textiles to achieve a rich red color in fabrics, with its fine particle size allowing for even distribution and color retention in various types of materials.
Used in Combination with Other Pigments:
Fast Red ITR is used in conjunction with other pigments to create specific shades of red, showcasing its versatility in color formulation and its compatibility with a range of colorants.
Used for Environmentally Friendly Applications:
Recognized for its non-toxic and environmentally friendly nature, Fast Red ITR is favored in applications where eco-friendliness is a priority, such as in the production of consumer products that minimize environmental impact.

InChI:InChI=1/C11H18N2O3S/c1-4-13(5-2)17(14,15)9-6-7-11(16-3)10(12)8-9/h6-8H,4-5,12H2,1-3H3

Upstream product

• 22117-79-9 4-methoxy-3-nitrobenzene-1-sulfonyl chloride 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 

Downstream Products

• 15939-76-1 5-(2-Methoxy-5-diethylsulfamoylphenylazo)-6-hydroxychrysen 
• 628736-16-3 3-[(4-chlorophenyl)thio]-N,N-diethyl-7-methoxy-2-methyl-1H-indole 
• 628736-15-2 3-[(4-chlorophenyl)thio]-4-[(diethylamino)sulfonyl]-7-methoxy-2-methyl-1H-indole-1-acetic acid 
• 628736-17-4 3-[(4-chlorophenyl)thio]-4-[(diethylamino)sulfonyl]-7-methoxy-2-methyl-1H-indole-1-acetic acid, methyl ester 
• 1432742-55-6 N-(2-tolyl)-3-amino-N,N-diethyl-4-methoxybenzenesulfonamide 
• 6837-92-9 3-amino-N,N-diethyl-4-hydroxybenzenesulfonamide 

Relevant academic research and scientific papers

CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS

Compounds of formula (1) or (2) and their use in the treatment of diseases or conditions for which a bromodomain inhibitor is indicated.

4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines

Various malignant human diseases show disturbed signaling pathways due to increased activity of proteins within the epigenetic machinery. Recently, various novel inhibitors for epigenetic regulation have been introduced which promise a great therapeutic benefit. Inhibitors for the bromo- and extra-terminal domain (BET) family were of particular interest after inhibitors had shown a strong antiproliferative effect. More recently, the focus has increasingly shifted to bromodomains (BDs) outside the BET family. Based on previously developed inhibitors, we have optimized a small series of 4-acyl pyrroles, which we further analyzed by ITC, X-ray crystallography, selectivity studies, the NCI60 cell-panel, and GI50 determinations for several cancer cell lines. The inhibitors address both, BET and BRD7/9 BDs, with very high affinity and show a strong antiproliferative effect on various cancer cell lines that could not be observed for BD family selective inhibitors. Furthermore, a synergistic effect on breast cancer (MCF-7) and melanoma (SK-MEL-5) was proven.

Metallized phenyl-azo-naphthol compounds

Metallized azo dyes of the formula STR1 wherein A is a sulfonyl, sulfonamido or carboxamido group, D is the residue of a phenol or naphthol, E is the residue of acetoacetanilide, a phenyl or naphthyl pyrazolone or the residue of a naphthol and M is a cation. The dyes are suitable for dyeing natural and synthetic polyamides, demonstrating good all-around fastness properties.

One step diazotization coupling process

A process for producing metal-free azo pigments in purely organic liquid or aqueous/organic liquid containing at most 10% of water calculated on the total weight of the suspension is described. In this one-step process, a suitable aromatic amine is diazotized without isolation of the obtained diazo compound and coupled with a coupling component. Both reactions are carried out in purely or essentially organic medium. The latter consists essentially of such amount of an organic liquid that a substantial portion either of the diazo component or of the coupling component or of both these reactants remain undissolved. Both reactants must be free from sulphonic acid groups. If the resulting azo pigment contains carboxylic acid groups, these can be subsequently converted to the corresponding amido or ester groups.