97026-73-8

Upstream product

• 92494-37-6 3-(2-chloro-phenyl)-5-propyl-isoxazole-4-carboxylic acid ethyl ester 
• 29568-74-9 2-chloro-N-hydroxybenzimidoyl chloride 
• 75-03-6 ethyl iodide 
• 23598-72-3 3-(2-chlorophenyl)-5-methyl-4-isoxazolecarboxylic acid 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists

A series of 3-aryl-4-isoxazolecarboxamides identified from a high-throughput screening campaign as novel, potent agonists of the human TGR5 G-protein-coupled receptor is described. Many analogues were readily accessible via solution-phase synthesis which