97038-01-2

Upstream product

• 30752-15-9 5-methyl-2-phenylbenzo[b][1,4]thiazepin-4(5H)-one 
• 29476-22-0 2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-one 
• 74-88-4 methyl iodide 
• 137-07-5 2-amino-benzenethiol 
• 5667-03-8 2-phenylbenzo[b][1,4]thiazepin-4(5H)-one 
• 637-44-5 phenylpropyolic acid 
• 140-10-3 (E)-3-phenylacrylic acid 

Downstream Products

• 120-75-2 2-Methylbenzothiazole 
• 2584-37-4 1-methyl-4-phenyl-1H-quinolin-2-one 
• 98-86-2 acetophenone 
• 145603-14-1 5-Methyl-1-oxo-2-phenyl-1,2,3,5-tetrahydro-1λ⁴-benzo[b][1,4]thiazepin-4-one 
• 145603-20-9 5-Methyl-1,1-dioxo-2-phenyl-1,2,3,5-tetrahydro-1λ⁶-benzo[b][1,4]thiazepin-4-one 

Relevant academic research and scientific papers

Asymmetric Hydrogenation of Vinylthioethers: Access to Optically Active 1,5-Benzothiazepine Derivatives

A novel asymmetric hydrogenation of vinylthioethers was developed using a ruthenium(II) NHC complex. This method provides an efficient approach to optically active 1,5-benzothiazepines featuring stereocenters with C-S bonds. Excellent enantioselectivities

Oxazepines and thiazepines, XXV: Chemical transformations of 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones

2,3-Dihydro-1,5-benzothiazepine-4(5H)-thiones 13-22 were prepared by the reaction of the appropriate 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones with Lawesson's reagent. N-Acyl (23-25) and N-alkyl (26-28) derivatives have also been synthesized. Oxidation wi

Synthesis, antibacterial and antifungal activities of several new benzo- naphtho- and quinolino-1,4-thiazine and 1,5-thiazepine derivatives

The synthesis of a number of thiosemicarbazone, phenylthiosemicarbazone, oxime and oxime O-ester derivatives of benzo- naphtho- and quinolino-1,4-thiazines and 1,5-thiazepines is described.All the compounds were tested in vitro for their antimicrobial act

Rearrangements and Complex Eliminations with 1,5-Benzothiazepin-4-ones

The 1,5-benzothiazepin-4-ones 3, 5, and 7 - 10 are pyrolyzed (with proton catalysis in part).New or rarely documented rearrangements and complex eliminations occur.These are classified and mechanistically discussed.The products and by-products are spectroscopically characterized (IR, UV, NMR, MS).Their configurations are elucidated via photolysis experiments. 4 photodimerizes in solution and in the crystalline state with great ease to give 14. 11 is remarkably insensitive towards hydrolysis.