97051-27-9

Upstream product

• 24028-40-8 5-phenyl-1,3,4-thiadiazolin-2-one 
• 106-96-7 propargyl bromide 
• 97051-23-5 2-ethylsulfonyl-5-phenyl-1,3,4-thiadiazole 

Downstream Products

• 97051-10-0 3-[4-(4-Methyl-piperazin-1-yl)-but-2-ynyl]-5-phenyl-3H-[1,3,4]thiadiazol-2-one; hydrochloride 
• 97051-09-7 3-(4-Azepan-1-yl-but-2-ynyl)-5-phenyl-3H-[1,3,4]thiadiazol-2-one; hydrochloride 
• 97051-07-5 3-[4-(2-Methyl-piperidin-1-yl)-but-2-ynyl]-5-phenyl-3H-[1,3,4]thiadiazol-2-one; hydrochloride 
• 134243-10-0 2-phenyl-4-iodopropargyl-1,3,4-thiadiazolin-5-one 
• 97051-08-6 3-[4-((2S,6R)-2,6-Dimethyl-piperidin-1-yl)-but-2-ynyl]-5-phenyl-3H-[1,3,4]thiadiazol-2-one; hydrochloride 
• 97051-11-1 3-(4-Morpholin-4-yl-but-2-ynyl)-5-phenyl-3H-[1,3,4]thiadiazol-2-one 
• 97051-06-4 5-Phenyl-3-(4-piperidin-1-yl-but-2-ynyl)-3H-[1,3,4]thiadiazol-2-one 
• 97051-05-3 5-Phenyl-3-(4-pyrrolidin-1-yl-but-2-ynyl)-3H-[1,3,4]thiadiazol-2-one 

Relevant academic research and scientific papers

Halopropargyl compounds, compositions, uses and processes of preparation

Compounds of the formula STR1 wherein A is selected from the group consisting of hydrogen, alkyl, aryl, and heterocyclic; Y and Z are independently selected from the group consisting of O, S, and N--R; R is selected from the group consisting of hydrogen,

Synthesis and biological evaluation of 5-aryl-3-(4-tert-amino-2-butynyl)-1,3,4-thiadiazol-2 (3H)-ones

A series of 5-aryl-3-(4-tert-amino-2-butynyl)-1,3,4-thiadiazol-2 (3H)-ones has been prepared and investigated for blocking motor effects of oxotremorine in intact mice and for their antagonistic activity towards acetylcholine on isolated guinea pig ileal