24028-40-8Relevant academic research and scientific papers
Halopropargyl compounds, compositions, uses and processes of preparation
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, (2008/06/13)
Compounds of the formula STR1 wherein A is selected from the group consisting of hydrogen, alkyl, aryl, and heterocyclic; Y and Z are independently selected from the group consisting of O, S, and N--R; R is selected from the group consisting of hydrogen,
The Oxidation of 1-Thioaroylsemicarbazides
Kurzer, Frederick,Doyle, Kevin M.
, p. 1873 - 1880 (2007/10/02)
Oxidation of 1-thioaroylsemicarbazides by bromine or hydrogen peroxide yields bis(C-aryl-N-ureido)formimidoyl disulphides.As a novel class of the generally labile di-imidoyl disulphides, such products display unusual stability; however, upon acylation, me
Synthesis and biological evaluation of 5-aryl-3-(4-tert-amino-2-butynyl)-1,3,4-thiadiazol-2 (3H)-ones
Muhi-Eldeen,Eldine,Al-Jawad,et al.
, p. 33 - 36 (2007/10/02)
A series of 5-aryl-3-(4-tert-amino-2-butynyl)-1,3,4-thiadiazol-2 (3H)-ones has been prepared and investigated for blocking motor effects of oxotremorine in intact mice and for their antagonistic activity towards acetylcholine on isolated guinea pig ileal
Studies on organophosphorus compounds XLIX. An improved method for the preparation of 2,5-disubstituted 1,3,4-thiadiazoles and 1,3,4-thiadiazole-2(3H)-thiones
Rasmussen, P.B.,Pedersen, U.,Thomsen, I.,Yde, B.,Lawesson, S.O.
, p. 62 - 65 (2007/10/02)
The reaction of 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide (LR) with N,N'-diacylhydrazines and N-acyl-N'-ethoxycarbonyl hydrazines has been investigated.It is shown that 2,5-disubstituted-1,3,4-thiadiazoles and 5-phenyl-1,3,4-thiadiazole-2(3H)-thione are produced in good yields.However, in the case of N-acetyl-N'-ethoxycarbonylhydrazine a 2,3-dihydro-1,3,4,2-thiadiazaphosphole, X, is formed.The fragmentation patterns in the mass spectra of simple 2,5-disubstituted 1,3,4,-thiadiazoles, IIIa-f, are described.
Unsaturated Compounds containing Nitrogen. Part 4. Further Reactions of 1-Chloro-2,3-diazabutadienes with S-Nucleophiles
Flowers, William T.,Robinson, John F.,Taylor, David R.,Tipping, Anthony E.
, p. 349 - 355 (2007/10/02)
1-Chloro-1,4-diaryl-2,3-diazabutadienes (Ar1CCl=NN=CHAr2), prepared by the reaction of thionyl chloride with aroylhydrazones (Ar1CONHN=CHAr2), react with thiosemicarbazide or thiocarbohydrazide to give 2-arylidenehydrazino-5-aryl-1,3,4-thiadiazoles, and with potassium thiocyanate to give 1-thiocyanato-1,4-diaryl-2,3-diazabutadienes which isomerize thermally to arylideneamino-5-aryl-1,3,4-thiadiazoles. 1-Chloro-1,4-diphenyl-2,3-diazabutadiene reacts with potassium ethylxanthate to give a 1-ethylxanthyl-2,3-diazabutadiene which on pyrolysis yields 2,5-diphenyl-1,3,4-thiadiazole.
