97073-22-8

Basic information

• Product Name: 1-PIPERIDIN-2-YL-ETHANONE
• Synonyms: 1-PIPERIDIN-2-YL-ETHANONE;2-ACETYLPIPERIDINE;Ethanone, 1-(2-piperidinyl)- (9CI);1-Boc-Piperidin-2-yl-ethanone;1-(2-Piperidinyl)ethanone;Ethanone, 1-(2-piperidinyl)-;1-(piperidin-2-yl)ethan-1-one
• CAS NO: 97073-22-8
• Molecular Formula: C₇H₁₃NO
• Molecular Weight: 127.18
• Product Categories: ACETYLGROUP
• Mol File: 97073-22-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 201.6 °C at 760 mmHg
• Flash Point: 86.1 °C
• Appearance: /
• Density: 0.95 g/cm³
• Vapor Pressure: 0.305mmHg at 25°C
• Refractive Index: 1.445
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-PIPERIDIN-2-YL-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PIPERIDIN-2-YL-ETHANONE(97073-22-8)
• EPA Substance Registry System: 1-PIPERIDIN-2-YL-ETHANONE(97073-22-8)

Safety Data

• Hazardous Substances Data: 97073-22-8(Hazardous Substances Data)

Usage

General Description

1-PIPERIDIN-2-YL-ETHANONE, also known as N-(2-Oxo-piperidin-1-yl)acetamide, is a chemical compound with the molecular formula C7H13NO2. It is a white to pale yellow solid with a pungent odor, and is commonly used as an intermediate in the synthesis of pharmaceuticals, organic compounds, and agrochemicals. 1-PIPERIDIN-2-YL-ETHANONE is also used in the production of various types of polymers and resins. It is considered to be a versatile building block in organic synthesis due to its reactivity and ability to undergo a wide range of chemical transformations. 1-PIPERIDIN-2-YL-ETHANONE has been extensively studied and researched for its potential applications in the pharmaceutical industry, and is known to possess various biological activities, making it a valuable compound in drug discovery and development.

InChI:InChI=1/C7H13NO/c1-6(9)7-4-2-3-5-8-7/h7-8H,2-5H2,1H3

Upstream product

• 1122-62-9 2-acetylpyridine 
• 106318-66-5 1-(2-piperidyl)ethanone hydrochloride 

Downstream Products

• 106318-69-8 N-(o-chlorocinnamoyl)-2-acetylpiperidine 

Relevant articles and documents

NHC-stabilised Rh nanoparticles: Surface study and application in the catalytic hydrogenation of aromatic substrates

New Rh-NPs stabilised by N-Heterocyclic Carbenes (NHC) were synthesized by decomposition of [Rh(η3-C3H5)3] under H2 atmosphere and fully characterized. Surface studies by FT-IR and NMR spectroscopy employing isotopically labelled ligands were also performed. The Rh0.2 NPs are active catalysts in the reduction of various aromatic substrates. In the reduction of phenol, high selectivities to cyclohexanone or cyclohexanol were obtained depending on the reaction conditions. However, this catalytic system exhibited much lower activity in the hydrogenation of substituted phenols. Pyridine was easily hydrogenated under mild conditions and interestingly, the hydrogenation of 4-methyl and 4-trifluoromethylpyridine resulted slower than that of 2-methylpyridine. The hydrogenation of 1-(pyridin-2-yl)propan-2-one provided the β-enaminone 13a in high yield as a consequence of the partial reduction of the pyridine ring followed by isomerization. Quinoline could be either partially hydrogenated to 1,2,3,4-tetrahydroquinoline or fully reduced to decahydroquinoline by adjusting the reaction conditions.

New short and general synthesis of three key Maillard flavour compounds: 2-Acetyl-1-pyrroline, 6-acetyl-1,2,3,4-tetrahydropyridine and 5-acetyl-2,3-dihydro-4H-1,4-thiazine

A new general synthetic route towards three key Maillard flavour compounds, namely 2-acetyl-1-pyrroline, 6-acetyl-1,2,3,4-tetrahydropyridine and 5-acetyl-2,3-dihydro-4H-1,4-thiazine, was developed. The key step in the process is the methylenation reaction of azaheterocyclic carboxylic esters by means of dimethyltitanocene, giving rise to intermediate vinyl ethers which can be considered as excellent and stable precursors for the title compounds, as a simple acidic treatment of these precursors suffices to release the characteristic Maillard flavours.