97135-92-7

Upstream product

• 109133-98-4 2,3-dimethyl-6-nitrobenzylamine 
• 59146-96-2 2,3-dimethyl-6-nitroaniline 
• 52911-60-1 2,3-dimethyl-6-nitrobenzonitrile 

Downstream Products

• 109133-81-5 (Z)-5-<(2,3-dimethyl-6-nitrophenyl)methylene>-2,3-imidazolidinedione 
• 109133-79-1 5-[1-(2,3-Dimethyl-6-nitro-phenyl)-meth-(Z)-ylidene]-1-methyl-imidazolidine-2,4-dione 
• 109133-82-6 2,3-dimethyl-6-nitrobenzaldehyde 

Relevant academic research and scientific papers

JAK2 AND ALK2 INHIBITORS AND METHODS FOR THEIR USE

Compounds having activity as inhibitors of ALK2 kinase and/or JAK2 kinase are disclosed. The compounds have the following structure (I): [FORMULA SHOULD BE INSERTED HERE] including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, X, z and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones - Inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation

A series of 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives was synthesized and evaluated as inhibitors of cAMP hydrolysis by a crude human platelet phosphodiesterase preparation and as inhibitors of ADP- and collagen-induced aggregation of rabbit

Imidazoquinoline antithrombrogenic cardiotonic agents

Novel series of 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones of the Formula STR1 wherein R1 is halogen, lower alkyl, lower alkoxy, trifluoromethyl; R2 is hydrogen, halogen, lower alkyl, lower alkoxy; R3 is hydrogen, haloge