97147-24-5

Upstream product

• 108-48-5 2,6-dimethylpyridine 
• 118668-51-2 1,3-dibromo-2-(tert-butylsulfonyl)-propane 

Downstream Products

• 118668-49-8 5-tert-butylsulfonyl-3-methyl-1-(2,6,6-trimethyl-1-cyclohexenyl)1,5 hexadien-3-ol 
• 97146-79-7 2-(2'-t-butylsulfonyl-2'-propenyl)-1-cyclohexanone 
• 97779-24-3 2-tert-butylsulfonyl-4 cyclohexyl-1-buten-4-one 
• 97779-17-4 1-phenyl-3-tert butylsulfonyl-3-buten-1-ol 
• 97146-77-5 2-t-butylsulfonyl-3-thiophenyl-1 propene 
• 118668-46-5 2-t-butylsulfonyl-3-(N-phenylamino)-1-propene 
• 101822-43-9 2-tert-butylsulfonyl-4-phenyl-4(N-phenylamino)-1-butene 
• 97779-38-9 5-tert-butylsulfonyl-6-phenyl-2,2-dimethyl-3-hexanone 
• 97779-31-2 5-tert-butylsulfonyl-6-phenyl-2,2-dimethyl-3-hexanol 
• 412010-89-0 4-(2-Methyl-propane-2-sulfonyl)-2-phenyl-nonan-2-ol 
• 97146-87-7 2-t-butylsulfonyl-5-methyl-1-phenyl-4-hexene 
• 97146-90-2 2-(tert-butylsulfonyl)-3-(phenylsulfonyl)-propene 
• 101822-42-8 4-(2-Methyl-propane-2-sulfonyl)-1,2-diphenyl-pyrrolidine 
• 97146-82-2 2-t-butylsulfonyl-3-phenyl-1-propene 

Relevant academic research and scientific papers

Synthesis and use of amino acid fluorides as peptide coupling reagents

The present invention is directed to the process of preparing a peptide comprising reacting a first amino acid or peptide with an amino acid fluoride of the formula: STR1 or the acid fluoride salts thereof wherein BLK is an N-amino protecting group AA is an amino acid residue and X is H or a protecting group useful, and the first amino and peptide have a free amino group and a blocked carboxy end.

Synthesis and use of amino acid fluorides as peptide coupling reagents

A compound of the formula STR1 or the acid fluoride salts thereof wherein BLK is an N-amino protecting group or hydrogenAA is an amino acid residue andX is H or a protecting group useful as a coupling agent in peptide synthesis.

Reagents for rapid peptide synthesis

This invention relates to compounds of the formula: STR1 wherein R is an electron withdrawing group; R1 is H or COZ; X1 and X2 are independently H, lower alkyl, aryl, aryl lower-alkyl or polystyrene or R and X1 taken together with the carbon atoms to which they are attached form a ring containing from 4 to 15 ring carbon atoms and may contain up to 2 heteroatoms, wherein the heteroatoms are O, S, or N; and Z is an amino acid residue, a peptide residue or a leaving group. The compounds of the present invention are adaptable as blocking or protecting groups for an amine composition useful in peptide synthesis. The present invention is also directed to a method of protecting an amino group of an organic molecule during a reaction which modifies a portion of the molecule other than the protected amino group.