Cefodizime, also known as (E)-Cefodizime, is a semi-synthetic cephalosporin antibiotic derived from cephalosporin C. It is characterized by its broad-spectrum antimicrobial activity and is effective against a wide range of Gram-negative and some Gram-positive bacteria. Cefodizime possesses a unique chemical structure that allows it to penetrate bacterial cell walls and inhibit bacterial cell wall synthesis, leading to bacterial cell death.
Source:
Cefodizime can be obtained from Ethyl Acetate (E899545), which is a chemical intermediate used in the production of various analgesics, antibiotics, and antimalarial agents.
Production Methods:
The synthesis of Cefodizime involves the modification of the cephalosporin C nucleus through various chemical reactions, including the introduction of a 7α-methoxy group and the replacement of the 3'-amino group with a 2-(2-amino-4-thiazolyl)-2-methoxyiminoacetyl group.
Source:
Cefodizime can be obtained from Ethyl Acetate (E899545), which is a chemical intermediate used in the production of various analgesics, antibiotics, and antimalarial agents.
Production Methods:
The synthesis of Cefodizime involves the modification of the cephalosporin C nucleus through various chemical reactions, including the introduction of a 7α-methoxy group and the replacement of the 3'-amino group with a 2-(2-amino-4-thiazolyl)-2-methoxyiminoacetyl group.
97180-26-2
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Basic information
- Product Name: Cefodizime
- Synonyms: E-Cefodizime impurity;[6R-[6α,7β(E)]]-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;(E)-Cefodizime
- CAS NO:97180-26-2
- Molecular Formula: C20H20N6O7S4
- Molecular Weight: 584.67
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: 1.86±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
- Solubility: DMSO (Slightly)
- PKA: 2.47±0.50(Predicted)
- CAS DataBase Reference: Cefodizime(CAS DataBase Reference)
- NIST Chemistry Reference: Cefodizime(97180-26-2)
- EPA Substance Registry System: Cefodizime(97180-26-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 97180-26-2(Hazardous Substances Data)
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97180-26-2 Usage
Uses
Used in Pharmaceutical Industry:Cefodizime is used as an antibiotic for the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and bone and joint infections. Its broad-spectrum activity and effectiveness against both Gram-negative and some Gram-positive bacteria make it a valuable therapeutic option for treating a wide range of infections.
Additionally, Cefodizime can be used in combination with other antibiotics to enhance the treatment of drug-resistant bacterial infections, improving patient outcomes and reducing the spread of antibiotic resistance.
Used in Research and Development:
Cefodizime is also used in research and development for the study of bacterial resistance mechanisms, the development of new antimicrobial agents, and the evaluation of novel drug delivery systems to improve the efficacy and safety of existing antibiotics. This research contributes to the advancement of antibiotic therapies and the fight against antibiotic resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 97180-26-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,1,8 and 0 respectively; the second part has 2 digits, 2 and 6 respectively.Calculate Digit Verification of CAS Registry Number 97180-26:
(7*9)+(6*7)+(5*1)+(4*8)+(3*0)+(2*2)+(1*6)=152
152 % 10 = 2
So 97180-26-2 is a valid CAS Registry Number.
97180-26-2Upstream product
97180-26-2Downstream Products
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Cefodizime
