97188-67-5

Upstream product

• 21305-56-6 3-methylthio-4-phenyl-1,2-dithiolium iodide 
• 1658-42-0 methyl 2-pyridylacetate 
• 103455-21-6 methyl (E)-2-phenyl-3-methoxy-2-propenate 
• 97188-66-4 methyl 3-phenyl-4-thio-4H-quinolizine-1-carboxylate 

Relevant academic research and scientific papers

Tricyclic pyridine derivatives and pharmaceutical compositions

Compounds of the formula STR1 or a pharmaceutically acceptable acid addition salt of a compound of formula I which has one or more basic substituents, are described. The compounds of formula I possess pronounced muscle relaxant, sedative-hypnotic, anticonvulsive and anxiolytic properties and have low toxicity.

The preparation of some fused isothiazole derivatives

The treatment of di(2-amino-5-methylphenyl)methane with N-sulfinylmethanesulfonamide gives two materials, 3-(2-amino-5-methylphenyl)-5-methyl-2,1-benzisothiazole and what appears to be its tautomer, a 2,1-benzisothiazolo-2,1-benzisothiazole derivative.Reaction of the former with methyl iodide gives mono-, di-, and trimethyl derivatives.The second of these also possesses the symmetrical 2,1-benzisothiazolo-2,1-benzisothiazole structure.The structure of the other methylation product and of the acetylation products are discussed.Some 1,2-dithiol-3-ylidene-2-pyridylmethanes were made by condensation of 3-alkylthio-1,2-dithiolium salts with methyl 2-pyridylacetate.These demonstrate little sulfur-nitrogen interaction. 3-Methylthio-4-phenyl-1,2-dithiolium iodide reacts anomalously with methyl 2-pyridylacetate to form a quinolizinethione. 1,2-Benzisothiazolopyridinium triiodide was made by iodine oxidation of 2-(2-mercaptophenylpyridine).