97191-89-4

Basic information

• Product Name: Benzamide, N,N'-[6-(bromomethyl)-2,4-quinazolinediyl]bis-
• CAS NO: 97191-89-4
• Molecular Formula: C23H17BrN4O2
• Molecular Weight: 461.318
• Mol File: 97191-89-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzamide, N,N'-[6-(bromomethyl)-2,4-quinazolinediyl]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N'-[6-(bromomethyl)-2,4-quinazolinediyl]bis-(97191-89-4)
• EPA Substance Registry System: Benzamide, N,N'-[6-(bromomethyl)-2,4-quinazolinediyl]bis-(97191-89-4)

Safety Data

• Hazardous Substances Data: 97191-89-4(Hazardous Substances Data)

Upstream product

• 1955-61-9 6-methyl-2,4-quinazolinediamine 
• 38939-88-7 2-chloro-4-methyl-1-nitrobenzene 
• 64113-86-6 2-nitro-5-methylbenzonitrile 
• 5925-93-9 2-amino-5-methylbenzonitrile 
• 95225-61-9 N,N'-(6-methyl-2,4-quinazolinediyl)bisbenzamide 

Downstream Products

• 111783-28-9 N,N'-<6-<<(4-chlorophenyl)(1-methylethyl)amino>methyl>-2,4-quinazolinediyl>bisbenzamide 
• 111783-29-0 N,N'-<6-<<(4-fluorophenyl)methylamino>methyl>-2,4-quinazolinediyl>bisbenzamide 
• 111783-27-8 C₃₀H₂₄BrN₅O₂ 
• 688056-37-3 2,4-dibenzamido-6-(p-methoxycarbonyl) phenylvinylquinazoline 
• 111783-35-8 6-{[Methyl-(3-trifluoromethyl-phenyl)-amino]-methyl}-quinazoline-2,4-diamine 
• 111783-48-3 6-{[(3,4-Dichloro-phenyl)-propyl-amino]-methyl}-quinazoline-2,4-diamine 
• 111783-42-7 6-{[(2,5-Dichloro-phenyl)-methyl-amino]-methyl}-quinazoline-2,4-diamine 
• 111783-47-2 6-{[(4-Bromo-phenyl)-ethyl-amino]-methyl}-quinazoline-2,4-diamine 
• 111783-30-3 6-{[(4-Chloro-phenyl)-ethyl-amino]-methyl}-quinazoline-2,4-diamine 
• 111783-40-5 6-{[(4-Chloro-phenyl)-methyl-amino]-methyl}-quinazoline-2,4-diamine 

Relevant articles and documents

Process for synthesizing antifolates

This invention relates to a process for synthesizing certain folic acid analogues, which are useful in treating cancer, inflammatory diseases, autoimmune diseases, and are commonly referred to as antifolates. The process employs improved steps for annulation, derivatization and addition reactions to produce the described antifolates from commonly available starting materials.