1955-61-9

Basic information

• Product Name: 6-Methyl-quinazoline-2,4-diamine
• Synonyms: 6-Methyl-quinazoline-2,4-diamine
• CAS NO: 1955-61-9
• Molecular Formula: C₉H₁₀N₄
• Molecular Weight: 174.2025
• Mol File: 1955-61-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 461.2°Cat760mmHg
• Flash Point: 263.7°C
• Appearance: /
• Density: 1.331g/cm³
• Vapor Pressure: 1.09E-08mmHg at 25°C
• Refractive Index: 1.755
• CAS DataBase Reference: 6-Methyl-quinazoline-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methyl-quinazoline-2,4-diamine(1955-61-9)
• EPA Substance Registry System: 6-Methyl-quinazoline-2,4-diamine(1955-61-9)

Safety Data

• Hazardous Substances Data: 1955-61-9(Hazardous Substances Data)

Usage

General Description

6-Methyl-quinazoline-2,4-diamine is a chemical compound with the molecular formula C9H10N4. It is a derivative of quinazoline, which is a heterocyclic compound. This chemical is commonly used in the pharmaceutical industry as a building block in the synthesis of various drugs and pharmaceuticals. Its primary application is in the development of anti-cancer drugs and as an antineoplastic agent. 6-Methyl-quinazoline-2,4-diamine has also shown potential in the treatment of other medical conditions, such as cardiovascular diseases and inflammatory disorders. Additionally, it has a wide range of bioactivities, including antiviral, antifungal, and antibacterial properties, making it a versatile and valuable compound in medical research and drug development.

InChI:InChI=1/C9H10N4/c1-5-2-3-7-6(4-5)8(10)13-9(11)12-7/h2-4H,1H3,(H4,10,11,12,13)

Upstream product

• 5925-93-9 2-amino-5-methylbenzonitrile 
• 127099-85-8 N-Cyanoguanidine 
• 593-85-1 guanidine carbonate 
• 64113-84-4 2-fluoro-5-methylbenzonitrile 
• 608-05-9 5-methyl-indole-2,3-dione 
• 42872-83-3 2-bromo-5-methylbenzylnitrile 
• 50-01-1 guanidine hydrochloride 
• 38939-88-7 2-chloro-4-methyl-1-nitrobenzene 
• 64113-86-6 2-nitro-5-methylbenzonitrile 

Downstream Products

• 72438-03-0 6-<<(4-fluorophenyl)methylamino>methyl>-2,4-quinazolinediamine 
• 98774-85-7 6-<<(4-bromophenyl)methylamino>methyl>-2,4-quinazolinediamine 
• 111783-37-0 6-{[(3-Chloro-phenyl)-methyl-amino]-methyl}-quinazoline-2,4-diamine 
• 111783-39-2 6-[(Ethyl-p-tolyl-amino)-methyl]-quinazoline-2,4-diamine 
• 72438-02-9 6-{[(2-Chloro-4-methyl-phenyl)-methyl-amino]-methyl}-quinazoline-2,4-diamine 
• 69827-77-6 6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-quinazoline-2,4-diamine 
• 98747-22-9 6-<<(4-chlorophenyl)(1-methylethyl)amino>methyl>-2,4-quinazolinediamine 
• 111783-38-1 6-{[Ethyl-(4-methoxy-phenyl)-amino]-methyl}-quinazoline-2,4-diamine 
• 111783-34-7 6-{[(3,4-Dichloro-phenyl)-isopropyl-amino]-methyl}-quinazoline-2,4-diamine 
• 98774-84-6 6-{[Ethyl-(3-trifluoromethyl-phenyl)-amino]-methyl}-quinazoline-2,4-diamine 
• 111783-45-0 6-{[(3,5-Bis-trifluoromethyl-phenyl)-methyl-amino]-methyl}-quinazoline-2,4-diamine 
• 111783-29-0 N,N'-<6-<<(4-fluorophenyl)methylamino>methyl>-2,4-quinazolinediyl>bisbenzamide 
• 111783-27-8 C₃₀H₂₄BrN₅O₂ 
• 111783-28-9 N,N'-<6-<<(4-chlorophenyl)(1-methylethyl)amino>methyl>-2,4-quinazolinediyl>bisbenzamide 

Relevant articles and documents

Fragment based search for small molecule inhibitors of HIV-1 Tat-TAR

Basic molecular building blocks such as benzene rings, amidines, guanidines, and amino groups have been combined in a systematic way to generate ligand candidates for HIV-1 TAR RNA. Ranking of the resulting compounds was achieved in a fluorimetric Tat-TAR

Efficient copper-catalyzed synthesis of 4-aminoquinazoline and 2,4-diaminoquinazoline derivatives

We have developed an efficient copper-catalyzed method for the synthesis of 4-aminoquinazoline and 2,4-diaminoquinazoline derivatives via reactions of substituted 2-bromobenzonitriles with amidines or guanidine, and the method is of economical and practic

Synthesis and antimalarial activity of a series of 2,4-diamino-6-[(N-alkylanilino)methyl]quinazolines

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