97211-00-2Relevant academic research and scientific papers
Diastereoselective Synthesis of γ-Amino Alcohols with Three Chiral Centers by Reduction of β-Amino Ketones and Derivatives
Barluenga, Jose,Olano, Bernardo,Fustero, Santos
, p. 4052 - 4056 (2007/10/02)
γ-Amino alcohols 4 with three chiral centers are obtained in very good yields by reduction of β-amino ketones 2 and β-acylamino ketones 3 with LiAlH4.The stereochemistry of the two diastereoisomers obtained in the reaction (4α and 4β) is unequivocally set
