97274-97-0

Upstream product

• 3464-61-7 6,β-bromo-4-cholesten-3-one 
• 563-63-3 silver(I) acetate 
• 3464-62-8 6α-bromo-cholest-4-en-3-one 
• 3702-37-2 4-bromocholest-4-en-3-one 
• 601-54-7 Cholest-5-en-3-one 

Downstream Products

• 566-93-8 cholesta-4,6-dien-3-one 
• 601-57-0 Cholest-4-en-3-one 

Relevant academic research and scientific papers

SILVER(1) ION CATALYZED SUBSTITUTION REACTIONS: STEREOELECTRONIC CONTROL IN AN SN1 MECHANISM

Stereochemistry of the acetolysis of 4- , 6α- , and 6β-bromocholest-4-en-3-ones using silver acetate was established, and the reactions were interpreted to proceed via a stereoelectronically controlled SN1 mechanism.

SYNTHESIS WITH MANGANIC SALTS; PART III: SYNTHESIS OF 1,4-DIKETONES THROUGH MANGANIC ACETATE-MEDIATED ADDITION OF KETONE TO ISOPENTENYL SULFONES. ACETOXYLATION OF Β,Γ-UNSATURATED KETONES BY MANGANOUS AND CUPRIC ACETATES

Conditions have been found to selectively add ketones to isopentenyl sulfones.The major product, a ketone bearing a methylene group at the γ position, gave upon ozonolysis the corresponding 1,4-diketone.The usefulness of the overall process was illustrated by the efficient syntheses of jasmone and of one half of pyrenophorine.The γ-acetoxy conjugated enones that invariably formed during these additions resulted from the oxidation of an isomeric β,γ-unsaturated ketone by manganous and cupric acetates.Such an acetoxylation has been used to prepare 6β-acetoxy-cholestenone from cholesterol and also to prepare chrysanthemic acid.