97276-81-8Relevant academic research and scientific papers
Stereoselective synthesis of (2E,4Z)-dienamides employing (triphenylphosphoranylidene)ketene
Pachali, Steffen,Hofmann, Christine,Rapp, Georg,Schobert, Rainer,Baro, Angelika,Frey, Wolfgang,Laschat, Sabine
supporting information; experimental part, p. 2828 - 2835 (2009/09/29)
The three-component reaction between ylide Ph3PCCO, amines and aldehydes is known to afford selectively (￡)-a,ssunsaturated amides. We applied a variant of this methodology to the preparation of (2B,4Z)-dienamides 11 utilizing the phosphonium s
Regio- and diastereoselective SN2′ or SN2″ reactions on chiral acetals of cyclic aldehydes promoted by PhCu, BF3
Maze, Frederique,Purpura, Martin,Bernaud, Frederic,Mangeney, Pierre,Alexakis, Alexandre
, p. 1957 - 1960 (2007/10/03)
The regio- and diastereoselectivity of the addition of PhCu, BF3 reagent on chiral acetals derived from several mono or dienic aldehydes was studied. It was found that monoethylenic acetals react regio- and diastereoselectively via an overall a
Design, synthesis, and application of a C2 symmetric chiral ligand for enantioselective conjugate addition of organolithium to α,β-unsaturated aldimine
Shindo, Mitsuru,Koga, Kenji,Tomioka, Kiyoshi
, p. 9351 - 9357 (2007/10/03)
A C2 symmetric chiral diether ligand, (1R,2R)-1,2-dimethoxy-1,2- diphenylethane, was designed and synthesized on the basis of the concept of an asymmetric oxygen atom. Mediated by the chiral diether, high enantioselectivities were achieved in conjugate addition of organolithiums to naphthaldehyde imine and cyclic and acyclic α,β-unsaturated aldimines. The absolute configuration of the product is predictable by the model.
