97280-22-3

Upstream product

• 13726-52-8 diethyl N-(p-aminobenzoyl)-L-glutamate 
• 456-41-7 1-(Bromomethyl)-3-fluorobenzene 

Downstream Products

• 97280-36-9 (S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-(3-fluoro-benzyl)-amino]-benzoylamino}-pentanedioic acid 
• 97280-29-0 (S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-(3-fluoro-benzyl)-amino]-benzoylamino}-pentanedioic acid diethyl ester 

Relevant academic research and scientific papers

Quinazoline Antifolates Inhibiting Thymidylate Synthase: Variation of the N10 Substituent

The synthesis of 12 new 5,8-dideazafolates with isopropyl, cyclopropylmethyl, 2-fluoroethyl, carbamoylmethyl, phenacyl, 3-fluorobenzyl, 5-uracilylmethyl, carboxymethyl, 2-carboxyethyl, 3-cyanopropyl, 3-hydroxypropyl, and cyanomethyl substituents at N